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Tace Dmel_CG7908
Protein found in Drosophila melanogaster
tace
Tace-PB
CG7908-PA
tumor necrosis factor-alpha-converting enzyme
Tace-PA
CG7908 gene product from transcript CG7908-RB
CG7908-PB
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Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q9VAC5
part of
disintegrin domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9VAC5
Metallopeptidase, catalytic domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9VAC5
Peptidase M12B, ADAM/reprolysin, protein family
1 reference
based on heuristic
inferred from protein domain or family
ADAM10/ADAM17 catalytic domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
ADAM17, membrane-proximal domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
Disintegrin domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
Peptidase M12B, propeptide family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Drosophila melanogaster
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q9VAC5
encoded by
Tace
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q9VAC5
molecular function
metalloendopeptidase activity
determination method
IDA
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VAC5
determination method
IEA
retrieved
8 April 2019
stated in
Unidirectional Notch signaling depends on continuous cleavage of Delta
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VAC5
determination method
IDA
peptidase activity
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9VAC5
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VAC5
determination method
IEA
metallopeptidase activity
determination method
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9VAC5
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VAC5
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VAC5
determination method
IEA
hydrolase activity
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9VAC5
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VAC5
determination method
IEA
metal ion binding
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9VAC5
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VAC5
determination method
IEA
cell component
membrane
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9VAC5
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VAC5
determination method
IEA
integral component of membrane
determination method
IEA
ISS
2 references
retrieved
8 April 2019
stated in
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VAC5
determination method
ISS
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9VAC5
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VAC5
determination method
IEA
biological process
proteolysis
determination method
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9VAC5
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VAC5
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VAC5
determination method
IEA
membrane protein ectodomain proteolysis
determination method
IDA
ISS
2 references
retrieved
8 April 2019
stated in
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VAC5
determination method
ISS
retrieved
8 April 2019
stated in
Unidirectional Notch signaling depends on continuous cleavage of Delta
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VAC5
determination method
IDA
Notch signaling pathway
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Kuz and TACE can activate Notch independent of ligand
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VAC5
determination method
IMP
Notch receptor processing
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
kuzbanian-mediated cleavage of Drosophila Notch
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VAC5
determination method
IMP
has part(s)
Peptidase M12B, propeptide
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9VAC5
ADAM10/ADAM17 catalytic domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9VAC5
ADAM17, membrane-proximal domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9VAC5
Disintegrin domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9VAC5
Peptidase M12B, ADAM/reprolysin
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9VAC5
Identifiers
RefSeq protein ID
NP_651759
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
43558
NP_733334
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
43558
UniProt protein ID
Q9VAC5
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q9VAC5
Ensembl protein ID
FBpp0084916
1 reference
stated in
ensembl Release 106
Ensembl protein ID
FBpp0084916
FBpp0084917
1 reference
stated in
ensembl Release 106
Ensembl protein ID
FBpp0084917
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