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Buffy Dmel_CG8238
Protein found in Drosophila melanogaster
Buffy-PA
Buffy
CG8238-PA
CG8238 gene product from transcript CG8238-RA
48A-E Bcl-2-like
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Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q8T8Y5
part of
Blc2-like superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q8T8Y5
Bcl-2-related ovarian killer protein
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q8T8Y5
found in taxon
Drosophila melanogaster
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q8T8Y5
encoded by
Buffy
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q8T8Y5
molecular function
protein homodimerization activity
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8T8Y5
determination method
IBA
protein heterodimerization activity
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8T8Y5
determination method
IBA
cell component
mitochondrial outer membrane
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8T8Y5
determination method
IBA
endoplasmic reticulum
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
Molecular determinants of the subcellular localization of the Drosophila Bcl-2 homologues DEBCL and BUFFY.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8T8Y5
determination method
IDA
membrane
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q8T8Y5
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8T8Y5
determination method
IEA
integral component of membrane
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q8T8Y5
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8T8Y5
determination method
IEA
biological process
apoptotic process
determination method
ISS
NAS
2 references
retrieved
8 April 2019
stated in
Apoptosis-an introduction
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8T8Y5
determination method
NAS
retrieved
8 April 2019
stated in
The Drosophila bcl-2 family member dBorg-1 functions in the apoptotic response to UV-irradiation
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8T8Y5
determination method
ISS
intrinsic apoptotic signaling pathway in response to DNA damage
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8T8Y5
determination method
IBA
cellular response to starvation
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Effector caspase Dcp-1 and IAP protein Bruce regulate starvation-induced autophagy during Drosophila melanogaster oogenesis
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8T8Y5
determination method
IMP
programmed cell death
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
Death to flies: Drosophila as a model system to study programmed cell death
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8T8Y5
determination method
TAS
positive regulation of macroautophagy
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Effector caspase Dcp-1 and IAP protein Bruce regulate starvation-induced autophagy during Drosophila melanogaster oogenesis
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8T8Y5
determination method
IMP
ectopic germ cell programmed cell death
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Alternative germ cell death pathway in Drosophila involves HtrA2/Omi, lysosomes, and a caspase-9 counterpart
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8T8Y5
determination method
IMP
regulation of apoptotic process
determination method
IEA
TAS
2 references
retrieved
8 April 2019
stated in
Death to flies: Drosophila as a model system to study programmed cell death
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8T8Y5
determination method
TAS
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8T8Y5
determination method
IEA
negative regulation of apoptotic process
determination method
IGI
IMP
2 references
retrieved
8 April 2019
stated in
Buffy, a Drosophila Bcl-2 protein, has anti-apoptotic and cell cycle inhibitory functions
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8T8Y5
determination method
IMP
retrieved
8 April 2019
stated in
Buffy, a Drosophila Bcl-2 protein, has anti-apoptotic and cell cycle inhibitory functions
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8T8Y5
determination method
IGI
positive regulation of programmed cell death
determination method
IGI
IMP
2 references
retrieved
8 April 2019
stated in
grim promotes programmed cell death of Drosophila microchaete glial cells
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8T8Y5
determination method
IMP
retrieved
8 April 2019
stated in
grim promotes programmed cell death of Drosophila microchaete glial cells
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8T8Y5
determination method
IGI
extrinsic apoptotic signaling pathway in absence of ligand
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8T8Y5
determination method
IBA
Identifiers
RefSeq protein ID
NP_523702
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
36251
UniProt protein ID
Q8T8Y5
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q8T8Y5
Ensembl protein ID
FBpp0087182
1 reference
stated in
ensembl Release 106
Ensembl protein ID
FBpp0087182
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