Home
Random
Nearby
Log in
Settings
Donate
About Wikidata
Disclaimers
Search
(Q29819537)
Watch
English
HTRA2-related serine protease Dmel_CG8464
Protein found in Drosophila melanogaster
HtrA2
HTRA2-related serine protease
CG8464-PA
CG8464 gene product from transcript CG8464-RB
HtrA2-PA
CG8464-PB
serine protease HTRA2
high temperature requirement A2
HtrA2-PB
In more languages
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q9VFJ3
part of
peptidase S1C
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9VFJ3
PDZ superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9VFJ3
Peptidase S1, PA clan
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9VFJ3
PDZ domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Drosophila melanogaster
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q9VFJ3
encoded by
HtrA2
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q9VFJ3
molecular function
serine-type endopeptidase activity
determination method
IDA
IEA
IMP
5 references
retrieved
8 April 2019
stated in
Evolution of mitochondrial cell death pathway: Proapoptotic role of HtrA2/Omi in Drosophila.
GOA
curator
UniProt
UniProt protein ID
Q9VFJ3
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VFJ3
determination method
IMP
retrieved
8 April 2019
stated in
Drosophila Omi, a mitochondrial-localized IAP antagonist and proapoptotic serine protease.
GOA
curator
UniProt
UniProt protein ID
Q9VFJ3
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VFJ3
determination method
IMP
retrieved
8 April 2019
stated in
The interaction of DIAP1 with dOmi/HtrA2 regulates cell death in Drosophila
GOA
curator
UniProt
UniProt protein ID
Q9VFJ3
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VFJ3
determination method
IMP
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VFJ3
determination method
IEA
retrieved
8 April 2019
stated in
Drosophila Omi, a mitochondrial-localized IAP antagonist and proapoptotic serine protease.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VFJ3
determination method
IDA
protein binding
determination method
IPI
3 references
retrieved
8 April 2019
stated in
Evolution of mitochondrial cell death pathway: Proapoptotic role of HtrA2/Omi in Drosophila.
GOA
curator
UniProt
UniProt protein ID
Q9VFJ3
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VFJ3
determination method
IPI
retrieved
8 April 2019
stated in
The interaction of DIAP1 with dOmi/HtrA2 regulates cell death in Drosophila
GOA
curator
UniProt
UniProt protein ID
Q9VFJ3
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VFJ3
determination method
IPI
retrieved
8 April 2019
stated in
Rhomboid-7 and HtrA2/Omi act in a common pathway with the Parkinson's disease factors Pink1 and Parkin
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VFJ3
determination method
IPI
peptidase activity
determination method
IDA
IEA
3 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9VFJ3
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VFJ3
determination method
IEA
retrieved
8 April 2019
stated in
Drosophila HtrA2 is dispensable for apoptosis but acts downstream of PINK1 independently from Parkin
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VFJ3
determination method
IDA
retrieved
8 April 2019
stated in
The interaction of DIAP1 with dOmi/HtrA2 regulates cell death in Drosophila
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VFJ3
determination method
IDA
serine-type peptidase activity
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9VFJ3
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VFJ3
determination method
IEA
hydrolase activity
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9VFJ3
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VFJ3
determination method
IEA
cell component
mitochondrion
determination method
IDA
IEA
3 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9VFJ3
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VFJ3
determination method
IEA
retrieved
8 April 2019
stated in
The interaction of DIAP1 with dOmi/HtrA2 regulates cell death in Drosophila
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VFJ3
determination method
IDA
retrieved
8 April 2019
stated in
Rhomboid-7 and HtrA2/Omi act in a common pathway with the Parkinson's disease factors Pink1 and Parkin
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VFJ3
determination method
IDA
mitochondrial intermembrane space
determination method
IDA
IEA
4 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9VFJ3
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VFJ3
determination method
IEA
retrieved
8 April 2019
stated in
Evolution of mitochondrial cell death pathway: Proapoptotic role of HtrA2/Omi in Drosophila.
GOA
curator
UniProt
UniProt protein ID
Q9VFJ3
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VFJ3
determination method
IDA
retrieved
8 April 2019
stated in
The interaction of DIAP1 with dOmi/HtrA2 regulates cell death in Drosophila
GOA
curator
UniProt
UniProt protein ID
Q9VFJ3
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VFJ3
determination method
IDA
retrieved
8 April 2019
stated in
Drosophila Omi, a mitochondrial-localized IAP antagonist and proapoptotic serine protease.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VFJ3
determination method
IDA
cytosol
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
Drosophila Omi, a mitochondrial-localized IAP antagonist and proapoptotic serine protease.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VFJ3
determination method
IDA
Nebenkern
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
Loss-of-function analysis suggests that Omi/HtrA2 is not an essential component of the PINK1/PARKIN pathway in vivo
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VFJ3
determination method
IDA
membrane
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9VFJ3
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VFJ3
determination method
IEA
integral component of membrane
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9VFJ3
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VFJ3
determination method
IEA
mitochondrial membranes
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9VFJ3
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VFJ3
determination method
IEA
biological process
proteolysis
determination method
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9VFJ3
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VFJ3
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VFJ3
determination method
IEA
apoptotic process
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9VFJ3
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VFJ3
determination method
IEA
mitochondrion organization
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Drosophila HtrA2 is dispensable for apoptosis but acts downstream of PINK1 independently from Parkin
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VFJ3
determination method
IMP
spermatogenesis
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Loss-of-function analysis suggests that Omi/HtrA2 is not an essential component of the PINK1/PARKIN pathway in vivo
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VFJ3
determination method
IMP
ectopic germ cell programmed cell death
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Alternative germ cell death pathway in Drosophila involves HtrA2/Omi, lysosomes, and a caspase-9 counterpart
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VFJ3
determination method
IMP
regulation of apoptotic process
determination method
IMP
3 references
retrieved
8 April 2019
stated in
Evolution of mitochondrial cell death pathway: Proapoptotic role of HtrA2/Omi in Drosophila.
GOA
curator
UniProt
UniProt protein ID
Q9VFJ3
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VFJ3
determination method
IMP
retrieved
8 April 2019
stated in
Drosophila Omi, a mitochondrial-localized IAP antagonist and proapoptotic serine protease.
GOA
curator
UniProt
UniProt protein ID
Q9VFJ3
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VFJ3
determination method
IMP
retrieved
8 April 2019
stated in
The interaction of DIAP1 with dOmi/HtrA2 regulates cell death in Drosophila
GOA
curator
UniProt
UniProt protein ID
Q9VFJ3
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VFJ3
determination method
IMP
positive regulation of apoptotic process
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Drosophila Omi, a mitochondrial-localized IAP antagonist and proapoptotic serine protease.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VFJ3
determination method
IMP
positive regulation of cysteine-type endopeptidase activity
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
Drosophila Omi, a mitochondrial-localized IAP antagonist and proapoptotic serine protease.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VFJ3
determination method
IDA
has part(s)
PDZ domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9VFJ3
Identifiers
RefSeq protein ID
NP_001262565
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
41756
NP_650366
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
41756
UniProt protein ID
Q9VFJ3
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q9VFJ3
Ensembl protein ID
FBpp0082446
1 reference
stated in
ensembl Release 106
Ensembl protein ID
FBpp0082446
FBpp0303078
1 reference
stated in
ensembl Release 106
Ensembl protein ID
FBpp0303078
Sitelinks
Wikipedia
(0 entries)
edit
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
edit
Multilingual sites
(0 entries)
edit
