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Highwire Dmel_CG32592
Protein found in Drosophila melanogaster
CG32592-PA
hiw
CG32592 gene product from transcript CG32592-RB
highwire
hiw-PA
CG32592-PB
hiw-PB
In more languages
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Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q9NB71
part of
Zinc finger, RING/FYVE/PHD-type
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9NB71
Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9NB71
Galactose-binding-like domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9NB71
Immunoglobulin E-set
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9NB71
PHR domain superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9NB71
Zinc finger, RING-type, protein family
1 reference
based on heuristic
inferred from protein domain or family
PHR domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
APC10/DOC domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
Regulator of chromosome condensation, RCC1, protein family
1 reference
based on heuristic
inferred from protein domain or family
Filamin/ABP280 repeat-like, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Drosophila melanogaster
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q9NB71
encoded by
hiw
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q9NB71
molecular function
ubiquitin-protein transferase activity
determination method
ISS
1 reference
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9NB71
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NB71
determination method
ISS
protein binding
determination method
IPI
3 references
retrieved
9 May 2019
stated in
DFsn collaborates with Highwire to down-regulate the Wallenda/DLK kinase and restrain synaptic terminal growth
GOA
curator
UniProt
UniProt protein ID
Q9NB71
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NB71
determination method
IPI
retrieved
9 May 2019
stated in
Highwire regulates presynaptic BMP signaling essential for synaptic growth.
GOA
curator
UniProt
UniProt protein ID
Q9NB71
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NB71
determination method
IPI
retrieved
9 May 2019
stated in
Drosophila Rae1 controls the abundance of the ubiquitin ligase Highwire in post-mitotic neurons.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NB71
determination method
IPI
zinc ion binding
determination method
ISM
1 reference
retrieved
9 May 2019
stated in
Comprehensively surveying structure and function of RING domains from Drosophila melanogaster
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NB71
determination method
ISM
transferase activity
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9NB71
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NB71
determination method
IEA
metal ion binding
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9NB71
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NB71
determination method
IEA
cell component
plasma membrane
determination method
IDA
1 reference
retrieved
9 May 2019
stated in
Highwire regulates synaptic growth in Drosophila
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NB71
determination method
IDA
cell junction
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9NB71
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NB71
determination method
IEA
axon
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9NB71
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NB71
determination method
IEA
cytoplasmic vesicle
determination method
IDA
1 reference
retrieved
9 May 2019
stated in
Highwire regulates synaptic growth in Drosophila
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NB71
determination method
IDA
cell projection
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9NB71
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NB71
determination method
IEA
synapse
determination method
IEA
1 reference
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9NB71
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NB71
determination method
IEA
nucleus
determination method
IBA
1 reference
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NB71
determination method
IBA
biological process
transcription, DNA-templated
determination method
IEA
1 reference
retrieved
31 January 2018
stated in
GOA
curator
UniProt
UniProt protein ID
Q9NB71
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NB71&geneProductId=UniProtKB:Q9NB71
determination method
IEA
regulation of transcription, DNA-templated
determination method
IEA
1 reference
retrieved
31 January 2018
stated in
GOA
curator
UniProt
UniProt protein ID
Q9NB71
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NB71&geneProductId=UniProtKB:Q9NB71
determination method
IEA
autophagy
determination method
IDA
1 reference
retrieved
9 May 2019
stated in
Autophagy promotes synapse development in Drosophila
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NB71
determination method
IDA
long-term memory
determination method
IMP
1 reference
retrieved
9 May 2019
stated in
A permissive role of mushroom body α/β core neurons in long-term memory consolidation in Drosophila
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NB71
determination method
IMP
adult walking behavior
determination method
NAS
1 reference
retrieved
9 May 2019
stated in
The central complex and the genetic dissection of locomotor behaviour
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NB71
determination method
NAS
regulation of synaptic assembly at neuromuscular junction
determination method
IMP
TAS
3 references
retrieved
9 May 2019
stated in
The central complex and the genetic dissection of locomotor behaviour
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NB71
determination method
TAS
retrieved
9 May 2019
stated in
Highwire regulates synaptic growth in Drosophila
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NB71
determination method
IMP
retrieved
9 May 2019
stated in
Highwire function at the Drosophila neuromuscular junction: spatial, structural, and temporal requirements.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NB71
determination method
IMP
negative regulation of gene expression
determination method
IMP
1 reference
retrieved
9 May 2019
stated in
Drosophila Rae1 controls the abundance of the ubiquitin ligase Highwire in post-mitotic neurons.
GOA
curator
UniProt
UniProt protein ID
Q9NB71
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NB71
determination method
IMP
protein ubiquitination
determination method
IEA
ISS
2 references
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9NB71
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NB71
determination method
ISS
retrieved
9 May 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9NB71
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NB71
determination method
IEA
BMP signaling pathway
determination method
IPI
1 reference
retrieved
8 April 2019
stated in
Highwire regulates presynaptic BMP signaling essential for synaptic growth.
GOA
curator
UniProt
UniProt protein ID
Q9NB71
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NB71
determination method
IPI
negative regulation of BMP signaling pathway
determination method
IGI
2 references
retrieved
9 May 2019
stated in
Highwire regulates presynaptic BMP signaling essential for synaptic growth.
GOA
curator
UniProt
UniProt protein ID
Q9NB71
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NB71
determination method
IGI
retrieved
9 May 2019
stated in
Highwire regulates presynaptic BMP signaling essential for synaptic growth.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NB71
determination method
IGI
locomotion
determination method
NAS
1 reference
retrieved
9 May 2019
stated in
The central complex and the genetic dissection of locomotor behaviour
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NB71
determination method
NAS
negative regulation of synaptic assembly at neuromuscular junction
determination method
IGI
IMP
5 references
retrieved
9 May 2019
stated in
Highwire regulates presynaptic BMP signaling essential for synaptic growth.
GOA
curator
UniProt
UniProt protein ID
Q9NB71
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NB71
determination method
IMP
retrieved
9 May 2019
stated in
Drosophila Rae1 controls the abundance of the ubiquitin ligase Highwire in post-mitotic neurons.
GOA
curator
UniProt
UniProt protein ID
Q9NB71
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NB71
determination method
IMP
retrieved
9 May 2019
stated in
Independent pathways downstream of the Wnd/DLK MAPKKK regulate synaptic structure, axonal transport, and injury signaling
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NB71
determination method
IMP
retrieved
9 May 2019
stated in
DFsn collaborates with Highwire to down-regulate the Wallenda/DLK kinase and restrain synaptic terminal growth
GOA
curator
UniProt
UniProt protein ID
Q9NB71
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NB71
determination method
IGI
retrieved
9 May 2019
stated in
Drosophila Rae1 controls the abundance of the ubiquitin ligase Highwire in post-mitotic neurons.
GOA
curator
UniProt
UniProt protein ID
Q9NB71
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NB71
determination method
IGI
response to axon injury
determination method
IMP
1 reference
retrieved
9 May 2019
stated in
Rapid in vivo forward genetic approach for identifying axon death genes in Drosophila
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NB71
determination method
IMP
synapse organization
determination method
IDA
1 reference
retrieved
9 May 2019
stated in
Autophagy promotes synapse development in Drosophila
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NB71
determination method
IDA
regulation of terminal button organization
determination method
IMP
1 reference
retrieved
9 May 2019
stated in
Independent pathways downstream of the Wnd/DLK MAPKKK regulate synaptic structure, axonal transport, and injury signaling
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NB71
determination method
IMP
has part(s)
Filamin/ABP280 repeat-like
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9NB71
APC10/DOC domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9NB71
Zinc finger, RING-type
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9NB71
Regulator of chromosome condensation, RCC1
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9NB71
PHR
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9NB71
Identifiers
RefSeq protein ID
NP_001285258
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
32429
NP_511159
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
32429
UniProt protein ID
Q9NB71
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q9NB71
Ensembl protein ID
FBpp0073787
1 reference
stated in
ensembl Release 106
Ensembl protein ID
FBpp0073787
FBpp0311921
1 reference
stated in
ensembl Release 106
Ensembl protein ID
FBpp0311921
Sitelinks
Wikipedia
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Wikibooks
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Wikinews
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Wikiquote
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Wikisource
(0 entries)
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Wikiversity
(0 entries)
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Wikivoyage
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Wiktionary
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Multilingual sites
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