(Q29819972)

English

Unpaired 3 Dmel_CG33542

Protein found in Drosophila melanogaster

CG33542-PB
CG33542 gene product from transcript CG33542-RB
unpaired 3beta
outstretched-smalleye
upd homolog
unpaired
unpaired-3
small-eye
outstretched
upd3-PB
upd3
unpaired-3.3
Unpaired3
unpaired 3
unpaired-like protein 3

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Statements

1 reference

25 May 2022

1 reference

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q59E38

found in taxon

Drosophila melanogaster

1 reference

25 May 2022

1 reference

25 May 2022

1 reference

31 January 2018

Upd3--an ancestor of the four-helix bundle cytokines

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q59E38&geneProductId=UniProtKB:Q59E38

determination method

ISM

intracellular anatomical structure

1 reference

16 July 2018

Gene Ontology Consortium

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q59E38&geneProductId=UniProtKB:Q59E38

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q59E38

determination method

IEA

integral component of membrane

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q59E38

1 reference

31 January 2018

The UPD3 cytokine couples environmental challenge and intestinal stem cell division through modulation of JAK/STAT signaling in the stem cell microenvironment

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q59E38&geneProductId=UniProtKB:Q59E38

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q59E38

3 references

8 April 2019

Upd3--an ancestor of the four-helix bundle cytokines

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q59E38

8 April 2019

The UPD3 cytokine couples environmental challenge and intestinal stem cell division through modulation of JAK/STAT signaling in the stem cell microenvironment

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q59E38

8 April 2019

Differential activities of the Drosophila JAK/STAT pathway ligands Upd, Upd2 and Upd3.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q59E38

determination method

IDA

biological process

embryonic development via the syncytial blastoderm

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q59E38

1 reference

8 April 2019

The roles of JAK/STAT signaling in Drosophila immune responses

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q59E38

determination method

NAS

positive regulation of cell population proliferation

1 reference

8 April 2019

Drosophila EGFR pathway coordinates stem cell proliferation and gut remodeling following infection

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q59E38

determination method

IMP

regulation of signaling receptor activity

1 reference

8 April 2019

Gene Ontology Consortium

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q59E38

determination method

IEA

antimicrobial humoral response

1 reference

8 April 2019

Thicker than blood: conserved mechanisms in Drosophila and vertebrate hematopoiesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q59E38

determination method

TAS

intestinal stem cell homeostasis

1 reference

8 April 2019

The UPD3 cytokine couples environmental challenge and intestinal stem cell division through modulation of JAK/STAT signaling in the stem cell microenvironment

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q59E38

1 reference

8 April 2019

Differential activities of the Drosophila JAK/STAT pathway ligands Upd, Upd2 and Upd3.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q59E38

determination method

IDA

regulation of imaginal disc-derived wing size

1 reference

8 April 2019

Dissecting the mechanisms of Notch induced hyperplasia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q59E38

1 reference

8 April 2019

Pleiotropy of the Drosophila JAK pathway cytokine Unpaired 3 in development and aging

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q59E38

determination method

IMP

intestinal epithelial structure maintenance

1 reference

8 April 2019

Autocrine and paracrine unpaired signaling regulate intestinal stem cell maintenance and division

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q59E38

determination method

IMP

receptor signaling pathway via JAK-STAT

9 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q59E38

8 April 2019

The UPD3 cytokine couples environmental challenge and intestinal stem cell division through modulation of JAK/STAT signaling in the stem cell microenvironment

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q59E38

8 April 2019

Differential activities of the Drosophila JAK/STAT pathway ligands Upd, Upd2 and Upd3.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q59E38

8 April 2019

Autocrine and paracrine unpaired signaling regulate intestinal stem cell maintenance and division

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q59E38

8 April 2019

Differential activities of the Drosophila JAK/STAT pathway ligands Upd, Upd2 and Upd3.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q59E38

8 April 2019

Pleiotropy of the Drosophila JAK pathway cytokine Unpaired 3 in development and aging

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q59E38

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q59E38

8 April 2019

Differential activities of the Drosophila JAK/STAT pathway ligands Upd, Upd2 and Upd3.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q59E38

8 April 2019

Upd3--an ancestor of the four-helix bundle cytokines

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q59E38

determination method

IDA

Identifiers

1 reference

20 March 2022

1 reference

25 May 2022

1 reference

(Q29819972)

Unpaired 3 Dmel_CG33542

Statements

Identifiers

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