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(Q29820051)
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Midline Dmel_CG6634
Protein found in Drosophila melanogaster
neuromancer2
CG6634-PA
extra
mid-PB
mid
midline
lost in space
CG6634-PB
mid-PA
neuromancer 1
CG6634 gene product from transcript CG6634-RA
H15-related
neuromancer 2
In more languages
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q9VMR2
part of
p53-like transcription factor, DNA-binding
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9VMR2
Transcription factor, T-box
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9VMR2
T-box superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9VMR2
Transcription factor, T-box, conserved site, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Drosophila melanogaster
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q9VMR2
encoded by
mid
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q9VMR2
molecular function
RNA polymerase II transcription regulatory region sequence-specific DNA binding
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
The Tbx20 homolog Midline represses wingless in conjunction with Groucho during the maintenance of segment polarity
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VMR2
determination method
IDA
DNA-binding transcription repressor activity, RNA polymerase II-specific
determination method
IDA
IMP
2 references
retrieved
8 April 2019
stated in
The Tbx20 homolog Midline represses wingless in conjunction with Groucho during the maintenance of segment polarity
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VMR2
determination method
IMP
retrieved
8 April 2019
stated in
The Tbx20 homolog Midline represses wingless in conjunction with Groucho during the maintenance of segment polarity
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VMR2
determination method
IDA
DNA binding
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9VMR2
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VMR2
determination method
IEA
DNA-binding transcription factor activity
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VMR2
determination method
IEA
cell component
nucleus
determination method
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9VMR2
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VMR2
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VMR2
determination method
IEA
biological process
negative regulation of transcription by RNA polymerase II
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
The Tbx20 homolog Midline represses wingless in conjunction with Groucho during the maintenance of segment polarity
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VMR2
determination method
IMP
heart process
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
Transcription factor neuromancer/TBX20 is required for cardiac function in Drosophila with implications for human heart disease
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VMR2
determination method
IDA
transcription, DNA-templated
determination method
IEA
1 reference
retrieved
16 July 2018
stated in
GOA
curator
UniProt
UniProt protein ID
Q9VMR2
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VMR2&geneProductId=UniProtKB:Q9VMR2
determination method
IEA
regulation of transcription, DNA-templated
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VMR2
determination method
IEA
ganglion mother cell fate determination
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Ancestry-independent fate specification and plasticity in the developmental timing of a typical Drosophila neuronal lineage
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VMR2
determination method
IMP
axonogenesis
determination method
IMP
NAS
2 references
retrieved
8 April 2019
stated in
Neuronal guidance. A genetic perspective
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VMR2
determination method
NAS
retrieved
8 April 2019
stated in
Mutations that affect the length, fasciculation, or ventral orientation of specific sensory axons in the Drosophila embryo
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VMR2
determination method
IMP
axon guidance
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Midline governs axon pathfinding by coordinating expression of two major guidance systems
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VMR2
determination method
IMP
central nervous system development
determination method
IGI
IMP
2 references
retrieved
8 April 2019
stated in
Neuromancer1 and Neuromancer2 regulate cell fate specification in the developing embryonic CNS of Drosophila melanogaster
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VMR2
determination method
IMP
retrieved
8 April 2019
stated in
Neuromancer1 and Neuromancer2 regulate cell fate specification in the developing embryonic CNS of Drosophila melanogaster
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VMR2
determination method
IGI
heart development
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
The Drosophila melanogaster T-box genes midline and H15 are conserved regulators of heart development
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VMR2
determination method
IMP
gonad development
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Transcriptional regulation of Drosophila gonad formation.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VMR2
determination method
IMP
negative regulation of gene expression
determination method
IGI
IMP
2 references
retrieved
8 April 2019
stated in
Neuromancer1 and Neuromancer2 regulate cell fate specification in the developing embryonic CNS of Drosophila melanogaster
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VMR2
determination method
IMP
retrieved
8 April 2019
stated in
Neuromancer1 and Neuromancer2 regulate cell fate specification in the developing embryonic CNS of Drosophila melanogaster
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VMR2
determination method
IGI
neuroblast fate specification
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Functions of the segment polarity genes midline and H15 in Drosophila melanogaster neurogenesis
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VMR2
determination method
IMP
neuroblast development
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Functions of the segment polarity genes midline and H15 in Drosophila melanogaster neurogenesis
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VMR2
determination method
IMP
chorion-containing eggshell pattern formation
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Response to the dorsal anterior gradient of EGFR signaling in Drosophila oogenesis is prepatterned by earlier posterior EGFR activation
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VMR2
determination method
IMP
embryonic heart tube development
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Neuromancer Tbx20-related genes (H15/midline) promote cell fate specification and morphogenesis of the Drosophila heart
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VMR2
determination method
IMP
leg disc pattern formation
determination method
IGI
1 reference
retrieved
8 April 2019
stated in
The Tbx20 homologs midline and H15 specify ventral fate in the Drosophila melanogaster leg.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VMR2
determination method
IGI
regulation of cell fate specification
determination method
IGI
IMP
2 references
retrieved
8 April 2019
stated in
Muscle cell fate choice requires the T-box transcription factor midline in Drosophila
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VMR2
determination method
IMP
retrieved
8 April 2019
stated in
The Tbx20 homologs midline and H15 specify ventral fate in the Drosophila melanogaster leg.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VMR2
determination method
IGI
cardioblast cell fate commitment
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Neuromancer Tbx20-related genes (H15/midline) promote cell fate specification and morphogenesis of the Drosophila heart
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VMR2
determination method
IMP
positive regulation of transcription by RNA polymerase II
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
Ancestry-independent fate specification and plasticity in the developmental timing of a typical Drosophila neuronal lineage
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VMR2
determination method
IDA
neuron fate specification
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Ancestry-independent fate specification and plasticity in the developmental timing of a typical Drosophila neuronal lineage
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VMR2
determination method
IMP
regulation of cardioblast differentiation
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Tbx20-related genes, mid and H15, are required for tinman expression, proper patterning, and normal differentiation of cardioblasts in Drosophila
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VMR2
determination method
IMP
regulation of nervous system development
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Ancestry-independent fate specification and plasticity in the developmental timing of a typical Drosophila neuronal lineage
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VMR2
determination method
IMP
fasciculation of motor neuron axon
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Mutations that affect the length, fasciculation, or ventral orientation of specific sensory axons in the Drosophila embryo
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VMR2
determination method
IMP
has part(s)
Transcription factor, T-box, conserved site
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9VMR2
Identifiers
RefSeq protein ID
NP_001260096
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
33770
NP_608927
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
33770
UniProt protein ID
Q9VMR2
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q9VMR2
Ensembl protein ID
FBpp0078726
1 reference
stated in
ensembl Release 106
Ensembl protein ID
FBpp0078726
FBpp0302039
1 reference
stated in
ensembl Release 106
Ensembl protein ID
FBpp0302039
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