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Topoisomerase 3alpha Dmel_CG10123
Protein found in Drosophila melanogaster
Top3alpha
topoisomerase IIIa
Top3alpha-PA
topoisomerase IIIalpha
topoisomerase 3-alpha
topoisomerase 3alpha
CG10123 gene product from transcript CG10123-RA
Top 3alpha
Topoisomerase3alpha
CG10123-PA
In more languages
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q9NG98
part of
DNA topoisomerase, type IA
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9NG98
DNA topoisomerase, type IA, central region, subdomain 2
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9NG98
DNA topoisomerase, type IA, core domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9NG98
DNA topoisomerase, type IA, central region, subdomain 1
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9NG98
DNA topoisomerase, type IA, central region, subdomain 3
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9NG98
DNA topoisomerase, type IA, DNA-binding domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
DNA topoisomerase, type IA, zn finger, protein family
1 reference
based on heuristic
inferred from protein domain or family
Zinc finger, GRF-type, protein family
1 reference
based on heuristic
inferred from protein domain or family
DNA topoisomerase 3-like, TOPRIM domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
DNA topoisomerase, type IA, domain 2, protein family
1 reference
based on heuristic
inferred from protein domain or family
TOPRIM domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
DNA topoisomerase, type IA, central domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
DNA topoisomerase, type IA, active site, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Drosophila melanogaster
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q9NG98
encoded by
Top3alpha
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q9NG98
molecular function
DNA binding
determination method
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9NG98
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NG98
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NG98
determination method
IEA
DNA topoisomerase activity
determination method
IDA
IEA
3 references
retrieved
16 July 2018
stated in
GOA
curator
UniProt
UniProt protein ID
Q9NG98
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NG98&geneProductId=UniProtKB:Q9NG98
determination method
IEA
retrieved
16 July 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NG98&geneProductId=UniProtKB:Q9NG98
determination method
IEA
retrieved
16 July 2018
stated in
Drosophila melanogaster topoisomerase IIIalpha preferentially relaxes a positively or negatively supercoiled bubble substrate and is essential during development
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NG98&geneProductId=UniProtKB:Q9NG98
determination method
IDA
DNA topoisomerase type I (single strand cut, ATP-independent) activity
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NG98
determination method
IEA
zinc ion binding
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NG98
determination method
IEA
isomerase activity
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9NG98
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NG98
determination method
IEA
DNA topoisomerase activity
determination method
IBA
IDA
IEA
4 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9NG98
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NG98
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NG98
determination method
IEA
retrieved
8 April 2019
stated in
Drosophila melanogaster topoisomerase IIIalpha preferentially relaxes a positively or negatively supercoiled bubble substrate and is essential during development
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NG98
determination method
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NG98
determination method
IBA
cell component
nucleus
determination method
IDA
1 reference
retrieved
16 July 2018
stated in
Drosophila topo IIIalpha is required for the maintenance of mitochondrial genome and male germ-line stem cells
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NG98&geneProductId=UniProtKB:Q9NG98
determination method
IDA
chromosome
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NG98
determination method
IEA
mitochondrion
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
Drosophila topo IIIalpha is required for the maintenance of mitochondrial genome and male germ-line stem cells
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NG98
determination method
IDA
nucleus
determination method
IBA
IDA
2 references
retrieved
8 April 2019
stated in
Drosophila topo IIIalpha is required for the maintenance of mitochondrial genome and male germ-line stem cells
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NG98
determination method
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NG98
determination method
IBA
biological process
mitochondrial genome maintenance
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Drosophila topo IIIalpha is required for the maintenance of mitochondrial genome and male germ-line stem cells
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NG98
determination method
IMP
double-strand break repair via homologous recombination
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Template disruptions and failure of double Holliday junction dissolution during double-strand break repair in Drosophila BLM mutants
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NG98
determination method
IMP
DNA topological change
determination method
IBA
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NG98
determination method
IEA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NG98
determination method
IBA
tissue regeneration
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Identification and characterization of genes required for compensatory growth in Drosophila
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NG98
determination method
IMP
developmental growth
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Identification and characterization of genes required for compensatory growth in Drosophila
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NG98
determination method
IMP
has part(s)
Zinc finger, GRF-type
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9NG98
DNA topoisomerase 3-like, TOPRIM domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9NG98
DNA topoisomerase, type IA, central
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9NG98
DNA topoisomerase, type IA, DNA-binding domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9NG98
DNA topoisomerase, type IA, domain 2
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9NG98
DNA topoisomerase, type IA, zn finger
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9NG98
DNA topoisomerase, type IA, active site
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9NG98
TOPRIM domain
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/Q9NG98
Identifiers
RefSeq protein ID
NP_523602
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
35236
UniProt protein ID
Q9NG98
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
Q9NG98
Ensembl protein ID
FBpp0080787
1 reference
stated in
ensembl Release 106
Ensembl protein ID
FBpp0080787
Sitelinks
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