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Kruppel Dmel_CG3340
Protein found in Drosophila melanogaster
Kr
kuppel
kruppel
Kr-PB
krpple
CG3340-PA
lruppel
CG3340-PB
krueppel
irregular facets
Kr-PA
CG3340 gene product from transcript CG3340-RB
In more languages
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P07247
part of
Zinc finger C2H2 superfamily
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P07247
Zinc finger C2H2-type, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Drosophila melanogaster
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P07247
encoded by
Kr
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P07247
molecular function
DNA-binding transcription factor activity, RNA polymerase II-specific
determination method
IDA
2 references
retrieved
8 April 2019
stated in
Functional analysis of repressor binding sites in the iab-2 regulatory region of the abdominal-A homeotic gene
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07247
determination method
IDA
retrieved
8 April 2019
stated in
Activation and repression of transcription by the gap proteins hunchback and Krüppel in cultured Drosophila cells
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07247
determination method
IDA
nucleic acid binding
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07247
determination method
IEA
DNA binding
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P07247
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07247
determination method
IEA
DNA-binding transcription factor activity
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
Transcription factors bind thousands of active and inactive regions in the Drosophila blastoderm
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07247
determination method
IDA
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
determination method
IDA
1 reference
retrieved
21 June 2018
stated in
Functional analysis of repressor binding sites in the iab-2 regulatory region of the abdominal-A homeotic gene
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P07247&geneProductId=UniProtKB:P07247
determination method
IDA
sequence-specific DNA binding
determination method
IDA
3 references
retrieved
8 April 2019
stated in
The products of the Drosophila gap genes hunchback and Krüppel bind to the hunchback promoters
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07247
determination method
IDA
retrieved
8 April 2019
stated in
CtBP-independent repression in the Drosophila embryo
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07247
determination method
IDA
retrieved
8 April 2019
stated in
Activation and repression of transcription by the gap proteins hunchback and Krüppel in cultured Drosophila cells
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07247
determination method
IDA
metal ion binding
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P07247
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07247
determination method
IEA
cell component
nucleus
determination method
IDA
IEA
3 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P07247
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07247
determination method
IEA
retrieved
8 April 2019
stated in
Silencing of genes in cultured Drosophila neurons by RNA interference
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07247
determination method
IDA
retrieved
8 April 2019
stated in
Analysis of Krüppel protein distribution during early Drosophila development reveals posttranscriptional regulation
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07247
determination method
IDA
biological process
negative regulation of transcription by RNA polymerase II
determination method
IDA
TAS
3 references
retrieved
8 April 2019
stated in
Transcriptional repression: the long and the short of it.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07247
determination method
TAS
retrieved
8 April 2019
stated in
Functional analysis of repressor binding sites in the iab-2 regulatory region of the abdominal-A homeotic gene
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07247
determination method
IDA
retrieved
8 April 2019
stated in
Activation and repression of transcription by the gap proteins hunchback and Krüppel in cultured Drosophila cells
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07247
determination method
IDA
multicellular organism development
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P07247
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07247
determination method
IEA
zygotic determination of anterior/posterior axis, embryo
determination method
NAS
TAS
2 references
retrieved
8 April 2019
stated in
The evolution of arthropod segmentation mechanisms
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07247
determination method
TAS
retrieved
8 April 2019
stated in
Transcriptional repression: the long and the short of it.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07247
determination method
NAS
neuroblast fate determination
determination method
IEP
IMP
2 references
retrieved
8 April 2019
stated in
Drosophila neuroblasts sequentially express transcription factors which specify the temporal identity of their neuronal progeny
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07247
determination method
IMP
retrieved
8 April 2019
stated in
Drosophila neuroblasts sequentially express transcription factors which specify the temporal identity of their neuronal progeny
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07247
determination method
IEP
ganglion mother cell fate determination
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
Genetic control of Drosophila nerve cord development
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07247
determination method
TAS
axon guidance
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Axon guidance of Drosophila SNb motoneurons depends on the cooperative action of muscular Krüppel and neuronal capricious activities
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07247
determination method
IMP
ventral cord development
determination method
NAS
1 reference
retrieved
8 April 2019
stated in
Genetic control of Drosophila nerve cord development
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07247
determination method
NAS
Malpighian tubule morphogenesis
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
Developmental genetics of the Drosophila gut: specification of primordia, subdivision and overt-differentiation.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07247
determination method
TAS
muscle organ development
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
Myoblast fusion in Drosophila
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07247
determination method
TAS
negative regulation of gene expression
determination method
IDA
1 reference
retrieved
1 January 2018
stated in
Regulation of the retinal determination gene dachshund in the embryonic head and developing eye of Drosophila
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07247
determination method
IDA
regulation of hemocyte proliferation
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Genetic manipulation of AML1-ETO-induced expansion of hematopoietic precursors in a Drosophila model
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07247
determination method
IMP
segmentation
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P07247
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07247
determination method
IEA
trunk segmentation
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
The evolution of arthropod segmentation mechanisms
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07247
determination method
TAS
regulation of development, heterochronic
determination method
NAS
TAS
3 references
retrieved
8 April 2019
stated in
Control of developmental timing by micrornas and their targets
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07247
determination method
TAS
retrieved
8 April 2019
stated in
Control of developmental timing by small temporal RNAs: a paradigm for RNA-mediated regulation of gene expression
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07247
determination method
TAS
retrieved
8 April 2019
stated in
Heterochronic genes
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07247
determination method
NAS
negative regulation of transcription, DNA-templated
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
CtBP-independent repression in the Drosophila embryo
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07247
determination method
IDA
compound eye development
determination method
IMP
2 references
retrieved
8 April 2019
stated in
Mutations on the second chromosome affecting the Drosophila eye.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07247
determination method
IMP
retrieved
8 April 2019
stated in
Regulation of the retinal determination gene dachshund in the embryonic head and developing eye of Drosophila
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07247
determination method
IMP
Malpighian tubule bud morphogenesis
determination method
IGI
1 reference
retrieved
8 April 2019
stated in
Genetic regulation of patterned tubular branching in Drosophila.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07247
determination method
IGI
regulation of neurogenesis
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Neural Lineage Progression Controlled by a Temporal Proliferation Program.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07247
determination method
IMP
regulation of neural precursor cell proliferation
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Neural Lineage Progression Controlled by a Temporal Proliferation Program.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07247
determination method
IMP
has part(s)
Zinc finger C2H2-type
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P07247
Identifiers
RefSeq protein ID
NP_001261181
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
38012
NP_523867
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
38012
UniProt protein ID
P07247
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P07247
Ensembl protein ID
FBpp0305365
1 reference
stated in
ensembl Release 106
Ensembl protein ID
FBpp0305365
FBpp0072351
1 reference
stated in
ensembl Release 106
Ensembl protein ID
FBpp0072351
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