(Q29820535)

http://www.ebi.ac.uk/interpro/protein/O61267

SMAD/FHA domain superfamily

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O61267

Forkhead-associated (FHA) domain, protein family

1 reference

Protein kinase domain, protein family

1 reference

Protein kinase, ATP binding site, protein family

1 reference

Serine/threonine-protein kinase, active site, protein family

1 reference

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O61267

found in taxon

Drosophila melanogaster

1 reference

25 May 2022

1 reference

25 May 2022

1 reference

8 April 2019

protein serine/threonine kinase activity

IEA

4 references

8 April 2019

A novel Drosophila nuclear protein serine/threonine kinase expressed in the germline during its establishment.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O61267

8 April 2019

Protein kinases and phosphatases in the Drosophila genome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O61267

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O61267

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O61267

2 references

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O61267

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O61267

tau-protein kinase activity

IEA

1 reference

8 April 2019

A DNA damage-activated checkpoint kinase phosphorylates tau and enhances tau-induced neurodegeneration

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O61267

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O61267

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O61267

8 April 2019

A novel Drosophila nuclear protein serine/threonine kinase expressed in the germline during its establishment.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O61267

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O61267

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O61267

Drosophila melanogaster MNK/Chk2 and p53 regulate multiple DNA repair and apoptotic pathways following DNA damage

biological process

regulation of DNA repair

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O61267

A novel Drosophila nuclear protein serine/threonine kinase expressed in the germline during its establishment.

protein phosphorylation

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O61267

8 April 2019

Protein kinases and phosphatases in the Drosophila genome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O61267

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O61267

1 reference

8 April 2019

Ionizing radiation induces caspase-dependent but Chk2- and p53-independent cell death in Drosophila melanogaster

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O61267

activation of cysteine-type endopeptidase activity involved in apoptotic process

1 reference

8 April 2019

p53 directs focused genomic responses in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O61267

A novel Drosophila nuclear protein serine/threonine kinase expressed in the germline during its establishment.

germ cell development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O61267

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O61267

peptidyl-serine phosphorylation

IEA

1 reference

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O61267&geneProductId=UniProtKB:O61267

peptidyl-threonine phosphorylation

1 reference

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O61267&geneProductId=UniProtKB:O61267

oocyte karyosome formation

1 reference

8 April 2019

The Drosophila hus1 gene is required for homologous recombination repair during meiosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O61267

ectopic germ cell programmed cell death

IGI

1 reference

8 April 2019

Drosophila Chk2 and p53 proteins induce stage-specific cell death independently during oogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O61267

signal transduction in response to DNA damage

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O61267

mitotic DNA damage checkpoint signaling

1 reference

21 June 2018

Anaphase DNA bridges induced by lack of RecQ5 in Drosophila syncytial embryos

http://www.ebi.ac.uk/QuickGO/annotations?protein=O61267&geneProductId=UniProtKB:O61267

positive regulation of transcription by RNA polymerase II

IDA

1 reference

8 April 2019

Chk2 regulates irradiation-induced, p53-mediated apoptosis in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O61267

positive regulation of DNA-binding transcription factor activity

1 reference

8 April 2019

Chk2 regulates irradiation-induced, p53-mediated apoptosis in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O61267

cellular response to gamma radiation

1 reference

8 April 2019

Chk2 regulates irradiation-induced, p53-mediated apoptosis in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O61267

intrinsic apoptotic signaling pathway by p53 class mediator

1 reference

8 April 2019

Chk2 regulates irradiation-induced, p53-mediated apoptosis in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O61267

cellular response to X-ray

IGI

1 reference

8 April 2019

DNA damage-induced Lok/CHK2 activation compromises germline stem cell self-renewal and lineage differentiation.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O61267