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Ubiquitin conjugating enzyme 6 Dmel_CG2013
Protein found in Drosophila melanogaster
CG2013-PC
ubiquitin conjugating enzyme
CG2013 gene product from transcript CG2013-RA
ubiquitin conjugating enzyme 6
Ubc6-PC
Ubc6
CG2013-PA
Ubc6-PA
In more languages
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P25153
part of
Ubiquitin-conjugating enzyme/RWD-like
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P25153
Ubiquitin-conjugating enzyme E2 family
1 reference
based on heuristic
inferred from protein domain or family
Ubiquitin-conjugating enzyme, active site, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Drosophila melanogaster
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P25153
encoded by
Ubc6
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P25153
molecular function
nucleotide binding
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P25153
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25153
determination method
IEA
p53 binding
determination method
IPI
2 references
retrieved
8 April 2019
stated in
E2 ligase dRad6 regulates DMP53 turnover in Drosophila
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25153
determination method
IPI
retrieved
8 April 2019
stated in
E2 ligase dRad6 regulates DMP53 turnover in Drosophila
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25153
determination method
IPI
ubiquitin-protein transferase activity
determination method
ISS
1 reference
retrieved
8 April 2019
stated in
Dhr6, a Drosophila homolog of the yeast DNA-repair gene RAD6.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25153
determination method
ISS
ATP binding
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P25153
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25153
determination method
IEA
transferase activity
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P25153
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25153
determination method
IEA
protein domain specific binding
determination method
IPI
1 reference
retrieved
8 April 2019
stated in
E2 ligase dRad6 regulates DMP53 turnover in Drosophila
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25153
determination method
IPI
ubiquitin protein ligase binding
determination method
IBA
1 reference
retrieved
27 February 2018
stated in
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P25153&geneProductId=UniProtKB:P25153
determination method
IBA
ubiquitin protein ligase activity
determination method
IBA
1 reference
retrieved
27 February 2018
stated in
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P25153&geneProductId=UniProtKB:P25153
determination method
IBA
ubiquitin conjugating enzyme activity
determination method
IC
1 reference
retrieved
27 February 2018
stated in
E2 ligase dRad6 regulates DMP53 turnover in Drosophila
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P25153&geneProductId=UniProtKB:P25153
determination method
IC
ubiquitin conjugating enzyme activity
determination method
IBA
IC
2 references
retrieved
8 April 2019
stated in
E2 ligase dRad6 regulates DMP53 turnover in Drosophila
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25153
determination method
IC
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25153
determination method
IBA
cell component
nucleus
determination method
IDA
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P25153
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25153
determination method
IEA
retrieved
8 April 2019
stated in
E2 ligase dRad6 regulates DMP53 turnover in Drosophila
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25153
determination method
IDA
cytoplasm
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
E2 ligase dRad6 regulates DMP53 turnover in Drosophila
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25153
determination method
IDA
HULC complex
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25153
determination method
IBA
biological process
protein polyubiquitination
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25153
determination method
IBA
autophagy of mitochondrion
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Mutations in the intellectual disability gene Ube2a cause neuronal dysfunction and impair parkin-dependent mitophagy
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25153
determination method
IMP
DNA repair
determination method
IEA
IGI
2 references
retrieved
27 February 2018
stated in
Dhr6, a Drosophila homolog of the yeast DNA-repair gene RAD6.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P25153&geneProductId=UniProtKB:P25153
determination method
IGI
retrieved
27 February 2018
stated in
GOA
curator
UniProt
UniProt protein ID
P25153
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P25153&geneProductId=UniProtKB:P25153
determination method
IEA
cellular response to DNA damage stimulus
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P25153
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25153
determination method
IEA
centrosome cycle
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Genes required for mitotic spindle assembly in Drosophila S2 cells
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25153
determination method
IMP
protein ubiquitination
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P25153
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25153
determination method
IEA
histone ubiquitination
determination method
IBA
1 reference
retrieved
27 February 2018
stated in
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P25153&geneProductId=UniProtKB:P25153
determination method
IBA
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
E2 ligase dRad6 regulates DMP53 turnover in Drosophila
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25153
determination method
IMP
endocytic recycling
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
Mutations in the intellectual disability gene Ube2a cause neuronal dysfunction and impair parkin-dependent mitophagy
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25153
determination method
IMP
negative regulation of apoptotic process
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
E2 ligase dRad6 regulates DMP53 turnover in Drosophila
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25153
determination method
IMP
proteasome-mediated ubiquitin-dependent protein catabolic process
determination method
IMP
1 reference
retrieved
27 February 2018
stated in
E2 ligase dRad6 regulates DMP53 turnover in Drosophila
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P25153&geneProductId=UniProtKB:P25153
determination method
IMP
negative regulation of DNA damage response, signal transduction by p53 class mediator
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
E2 ligase dRad6 regulates DMP53 turnover in Drosophila
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25153
determination method
IMP
centrosome separation
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
A genome-wide RNAi screen to dissect centriole duplication and centrosome maturation in Drosophila.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25153
determination method
IMP
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
E2 ligase dRad6 regulates DMP53 turnover in Drosophila
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25153
determination method
IMP
ubiquitin-dependent protein catabolic process
determination method
IMP
1 reference
retrieved
8 April 2019
stated in
E2 ligase dRad6 regulates DMP53 turnover in Drosophila
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25153
determination method
IMP
DNA repair
determination method
IBA
IEA
IGI
3 references
retrieved
8 April 2019
stated in
Dhr6, a Drosophila homolog of the yeast DNA-repair gene RAD6.
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25153
determination method
IGI
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P25153
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25153
determination method
IEA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25153
determination method
IBA
proteasome-mediated ubiquitin-dependent protein catabolic process
determination method
IBA
IMP
2 references
retrieved
8 April 2019
stated in
E2 ligase dRad6 regulates DMP53 turnover in Drosophila
GOA
curator
FlyBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25153
determination method
IMP
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P25153
determination method
IBA
has part(s)
Ubiquitin-conjugating enzyme E2
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P25153
Ubiquitin-conjugating enzyme, active site
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/P25153
Identifiers
RefSeq protein ID
NP_001246916
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
40610
NP_524230
1 reference
stated in
NCBI Gene
retrieved
20 March 2022
Entrez Gene ID
40610
UniProt protein ID
P25153
1 reference
stated in
UniProt
retrieved
25 May 2022
UniProt protein ID
P25153
Ensembl protein ID
FBpp0297243
1 reference
stated in
ensembl Release 106
Ensembl protein ID
FBpp0297243
FBpp0078490
1 reference
stated in
ensembl Release 106
Ensembl protein ID
FBpp0078490
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