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FGFR1 Fusion
genetic variant
FGFR1 FUSIONS
Fusion
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Statements
instance of
transcript fusion
1 reference
stated in
CIViC database
retrieved
23 May 2022
reference URL
https://civic.genome.wustl.edu/links/variants/569
chromosome
human chromosome 8
genomic assembly
Genome assembly GRCh37
1 reference
stated in
CIViC database
retrieved
23 May 2022
reference URL
https://civic.genome.wustl.edu/links/variants/569
genomic start
38268656
genomic assembly
Genome assembly GRCh37
1 reference
stated in
CIViC database
retrieved
23 May 2022
reference URL
https://civic.genome.wustl.edu/links/variants/569
genomic end
38325363
genomic assembly
Genome assembly GRCh37
1 reference
stated in
CIViC database
retrieved
23 May 2022
reference URL
https://civic.genome.wustl.edu/links/variants/569
biological variant of
FGFR1
1 reference
stated in
CIViC database
retrieved
23 May 2022
reference URL
https://civic.genome.wustl.edu/links/variants/569
positive therapeutic predictor for
sunitinib
determination method
CIViC evidence level D
rating
CIViC 3-star trust rating
medical condition treated
acute myeloid leukemia
statement disputed by
Potent activity of ponatinib (AP24534) in models of FLT3-driven acute myeloid leukemia and other hematologic malignancies
1 reference
curator
CIViC database
retrieved
23 May 2022
reference URL
https://civic.genome.wustl.edu/links/evidence/7375
stated in
Potent activity of ponatinib (AP24534) in models of FLT3-driven acute myeloid leukemia and other hematologic malignancies
sorafenib
determination method
CIViC evidence level D
rating
CIViC 3-star trust rating
medical condition treated
acute myeloid leukemia
statement disputed by
Potent activity of ponatinib (AP24534) in models of FLT3-driven acute myeloid leukemia and other hematologic malignancies
1 reference
curator
CIViC database
retrieved
23 May 2022
reference URL
https://civic.genome.wustl.edu/links/evidence/7375
stated in
Potent activity of ponatinib (AP24534) in models of FLT3-driven acute myeloid leukemia and other hematologic malignancies
positive diagnostic predictor for
hematologic cancer
determination method
CIViC evidence level A
rating
CIViC 5-star trust rating
1 reference
curator
CIViC database
retrieved
23 May 2022
reference URL
https://civic.genome.wustl.edu/links/evidence/1435
stated in
The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia
negative diagnostic predictor for
chronic myelomonocytic leukemia
determination method
CIViC evidence level A
rating
CIViC 5-star trust rating
1 reference
curator
CIViC database
retrieved
23 May 2022
reference URL
https://civic.genome.wustl.edu/links/evidence/1427
stated in
The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia
Identifiers
CIViC variant ID
569
1 reference
stated in
CIViC database
retrieved
23 May 2022
reference URL
https://civic.genome.wustl.edu/links/variants/569
HGVS nomenclature
no value
1 reference
stated in
CIViC database
retrieved
23 May 2022
reference URL
https://civic.genome.wustl.edu/links/variants/569
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