(Q29938360)

English

KRAS A146P

genetic variant

A146P
RS121913527
ALA146PRO

In more languages

default for all languages

No label defined

No description defined

Statements

missense mutation

1 reference

28 March 2022

https://civic.genome.wustl.edu/links/variants/905

human chromosome 12

genomic assembly

Genome assembly GRCh37

1 reference

28 March 2022

https://civic.genome.wustl.edu/links/variants/905

25378562

genomic assembly

Genome assembly GRCh37

1 reference

28 March 2022

https://civic.genome.wustl.edu/links/variants/905

25378562

genomic assembly

Genome assembly GRCh37

1 reference

28 March 2022

https://civic.genome.wustl.edu/links/variants/905

biological variant of

1 reference

28 March 2022

https://civic.genome.wustl.edu/links/variants/905

negative therapeutic predictor for

irinotecan / Cetuximab combination therapy

determination method

CIViC evidence level C

CIViC 3-star trust rating

medical condition treated

colorectal cancer

1 reference

28 March 2022

https://civic.genome.wustl.edu/links/evidence/2225

KRAS codon 61, 146 and BRAF mutations predict resistance to cetuximab plus irinotecan in KRAS codon 12 and 13 wild-type metastatic colorectal cancer.

Identifiers

CIViC variant ID

1 reference

28 March 2022

https://civic.genome.wustl.edu/links/variants/905

dbSNP Reference SNP number

1 reference

HGVS nomenclature

NM_004985.4:c.436G>C

1 reference

28 March 2022

https://civic.genome.wustl.edu/links/variants/905

NP_004976.2:p.Ala146Pro

1 reference

28 March 2022

https://civic.genome.wustl.edu/links/variants/905

NC_000012.11:g.25378562C>G

1 reference

28 March 2022

https://civic.genome.wustl.edu/links/variants/905

ENST00000256078.4:c.436G>C

1 reference

28 March 2022

https://civic.genome.wustl.edu/links/variants/905

Sitelinks

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Multilingual sites(0 entries)

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