(Q29938722)

English

PIK3CA I391M

genetic variant

I391M
RS2230461
ILE391MET

In more languages

default for all languages

No label defined

No description defined

Statements

missense mutation

1 reference

28 March 2022

https://civic.genome.wustl.edu/links/variants/1235

human chromosome 3

genomic assembly

Genome assembly GRCh37

1 reference

28 March 2022

https://civic.genome.wustl.edu/links/variants/1235

178927410

genomic assembly

Genome assembly GRCh37

1 reference

28 March 2022

https://civic.genome.wustl.edu/links/variants/1235

178927410

genomic assembly

Genome assembly GRCh37

1 reference

28 March 2022

https://civic.genome.wustl.edu/links/variants/1235

biological variant of

1 reference

28 March 2022

https://civic.genome.wustl.edu/links/variants/1235

negative therapeutic predictor for

ado-trastuzumab emtansine

determination method

CIViC evidence level D

CIViC 3-star trust rating

medical condition treated

Her2-receptor positive breast cancer

statement disputed by

Relationship between Tumor Biomarkers and Efficacy in EMILIA, a Phase III Study of Trastuzumab Emtansine in HER2-Positive Metastatic Breast Cancer

1 reference

28 March 2022

https://civic.genome.wustl.edu/links/evidence/2867

Relationship between Tumor Biomarkers and Efficacy in EMILIA, a Phase III Study of Trastuzumab Emtansine in HER2-Positive Metastatic Breast Cancer

determination method

CIViC evidence level D

CIViC 2-star trust rating

medical condition treated

Her2-receptor positive breast cancer

statement disputed by

Relationship between Tumor Biomarkers and Efficacy in EMILIA, a Phase III Study of Trastuzumab Emtansine in HER2-Positive Metastatic Breast Cancer

1 reference

28 March 2022

https://civic.genome.wustl.edu/links/evidence/8663

Relationship between Tumor Biomarkers and Efficacy in EMILIA, a Phase III Study of Trastuzumab Emtansine in HER2-Positive Metastatic Breast Cancer

Identifiers

CIViC variant ID

1 reference

28 March 2022

https://civic.genome.wustl.edu/links/variants/1235

dbSNP Reference SNP number

1 reference

HGVS nomenclature

NM_006218.3:c.1173A>G

1 reference

28 March 2022

https://civic.genome.wustl.edu/links/variants/1235

NP_006209.2:p.Ile391Met

1 reference

28 March 2022

https://civic.genome.wustl.edu/links/variants/1235

NC_000003.11:g.178927410A>G

1 reference

28 March 2022

https://civic.genome.wustl.edu/links/variants/1235

ENST00000263967.3:c.1173A>G

1 reference

28 March 2022

https://civic.genome.wustl.edu/links/variants/1235

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q29938722&oldid=2014805732"