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TP53 Overexpression
genetic variant
Overexpression
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Statements
instance of
sequence variant
1 reference
stated in
CIViC database
retrieved
23 May 2022
reference URL
https://civic.genome.wustl.edu/links/variants/1306
chromosome
human chromosome 17
genomic assembly
Genome assembly GRCh37
1 reference
stated in
CIViC database
retrieved
23 May 2022
reference URL
https://civic.genome.wustl.edu/links/variants/1306
genomic start
7571720
genomic assembly
Genome assembly GRCh37
1 reference
stated in
CIViC database
retrieved
23 May 2022
reference URL
https://civic.genome.wustl.edu/links/variants/1306
genomic end
7590856
genomic assembly
Genome assembly GRCh37
1 reference
stated in
CIViC database
retrieved
23 May 2022
reference URL
https://civic.genome.wustl.edu/links/variants/1306
biological variant of
TP53
1 reference
stated in
CIViC database
retrieved
23 May 2022
reference URL
https://civic.genome.wustl.edu/links/variants/1306
positive therapeutic predictor for
etoposide / mitomycin / cisplatin combination therapy
determination method
CIViC evidence level B
rating
CIViC 4-star trust rating
medical condition treated
stomach cancer
1 reference
curator
CIViC database
retrieved
23 May 2022
reference URL
https://civic.genome.wustl.edu/links/evidence/2799
stated in
Alterations in p53 predict response to preoperative high dose chemotherapy in patients with gastric cancer
negative therapeutic predictor for
cisplatin
determination method
CIViC evidence level B
rating
CIViC 3-star trust rating
medical condition treated
ovarian cancer
1 reference
curator
CIViC database
retrieved
23 May 2022
reference URL
https://civic.genome.wustl.edu/links/evidence/3013
stated in
Correlation of p53 mutations with resistance to platinum-based chemotherapy and shortened survival in ovarian cancer.
carboplatin
determination method
CIViC evidence level B
rating
CIViC 3-star trust rating
medical condition treated
ovarian cancer
1 reference
curator
CIViC database
retrieved
23 May 2022
reference URL
https://civic.genome.wustl.edu/links/evidence/3013
stated in
Correlation of p53 mutations with resistance to platinum-based chemotherapy and shortened survival in ovarian cancer.
negative prognostic predictor for
ovarian cancer
determination method
CIViC evidence level B
rating
CIViC 3-star trust rating
1 reference
curator
CIViC database
retrieved
23 May 2022
reference URL
https://civic.genome.wustl.edu/links/evidence/2697
stated in
Correlation of p53 mutations with resistance to platinum-based chemotherapy and shortened survival in ovarian cancer.
renal Wilms' tumor
determination method
CIViC evidence level B
rating
CIViC 3-star trust rating
1 reference
curator
CIViC database
retrieved
23 May 2022
reference URL
https://civic.genome.wustl.edu/links/evidence/8945
stated in
Immunohistochemical detection of p53 protein expression as a prognostic factor in Wilms tumor
Identifiers
CIViC variant ID
1306
1 reference
stated in
CIViC database
retrieved
23 May 2022
reference URL
https://civic.genome.wustl.edu/links/variants/1306
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