(Q32965028)

English

ABL1 BCR::ABL F311L

genetic variant

F311L
BCR-ABL F311L
RS137853304
F330L
BCR-ABL PHE311LEU
BCR-ABL1 F311L
BCR-ABL1 PHE311LEU
BCR::ABL F311L

In more languages

default values for all languages

No label defined

No description defined

Statements

missense mutation

1 reference

28 March 2022

https://civic.genome.wustl.edu/links/variants/1528

transcript fusion

1 reference

28 March 2022

https://civic.genome.wustl.edu/links/variants/1528

human chromosome 9

genomic assembly

Genome assembly GRCh37

1 reference

28 March 2022

https://civic.genome.wustl.edu/links/variants/1528

133748270

genomic assembly

Genome assembly GRCh37

1 reference

28 March 2022

https://civic.genome.wustl.edu/links/variants/1528

133748270

genomic assembly

Genome assembly GRCh37

1 reference

28 March 2022

https://civic.genome.wustl.edu/links/variants/1528

biological variant of

1 reference

28 March 2022

https://civic.genome.wustl.edu/links/variants/1528

negative therapeutic predictor for

determination method

CIViC evidence level C

CIViC 2-star trust rating

medical condition treated

chronic myeloid leukemia

statement disputed by

Safety and efficacy of bosutinib (SKI-606) in chronic phase Philadelphia chromosome-positive chronic myeloid leukemia patients with resistance or intolerance to imatinib

1 reference

28 March 2022

https://civic.genome.wustl.edu/links/evidence/4546

Safety and efficacy of bosutinib (SKI-606) in chronic phase Philadelphia chromosome-positive chronic myeloid leukemia patients with resistance or intolerance to imatinib

imatinib mesylate / nilotinib combination therapy

determination method

CIViC evidence level D

CIViC 2-star trust rating

medical condition treated

chronic myeloid leukemia

1 reference

28 March 2022

https://civic.genome.wustl.edu/links/evidence/6238

Comparison of imatinib mesylate, dasatinib (BMS-354825), and nilotinib (AMN107) in an N-ethyl-N-nitrosourea (ENU)-based mutagenesis screen: high efficacy of drug combinations

Identifiers

CIViC variant ID

1 reference

28 March 2022

https://civic.genome.wustl.edu/links/variants/1528

dbSNP Reference SNP number

1 reference

HGVS nomenclature

NM_005157.5:c.931T>C

1 reference

28 March 2022

https://civic.genome.wustl.edu/links/variants/1528

NP_005148.2:p.Phe311Leu

1 reference

28 March 2022

https://civic.genome.wustl.edu/links/variants/1528

NC_000009.11:g.133748270T>C

1 reference

28 March 2022

https://civic.genome.wustl.edu/links/variants/1528

ENST00000318560.5:c.931T>C

1 reference

28 March 2022

https://civic.genome.wustl.edu/links/variants/1528

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q32965028&oldid=2014807112"