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English
NOTCH1 t(7;9)(NOTCH1:M1580_K2555) is cleaved to produce NEXT1
An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-2666278)
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Statements
instance of
biological process
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-2666278
part of
Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-2666278
found in taxon
Homo sapiens
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-2666278
exact match
https://identifiers.org/reactome:R-HSA-2666278
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-2666278
has part(s)
NOTCH1 t(7;9)(NOTCH1:M1580_K2555) [plasma membrane]
quantity
1
object has role
reactant
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-2666278
Notch receptor 1
quantity
1
object has role
product
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-2666278
NOTCH1 t(7;9)(NOTCH1:M1580_K2555) fragment [extracellular region]
quantity
1
object has role
product
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-2666278
ADAM10/17:Zn2+ [plasma membrane]
quantity
1
object has role
modifier
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-2666278
cites work
TAN-1, the human homolog of the Drosophila Notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-2666278
Identifiers
Reactome ID
R-HSA-2666278
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-2666278
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