Wikidata

(Q421219)

English

Thioredoxin

mammalian protein found in Homo sapiens

  • TXN delta 3
  • testicular tissue protein Li 199
  • thioredoxin delta 3
  • thioredoxin
  • TXN
  • ATL-derived factor
  • ADF
  • SASP
  • surface-associated sulphydryl protein
In more languages

Statements

molecular function
protein binding
determination method
IPI
16 references
retrieved
8 April 2019
stated in
Salmonella type III secretion effector SlrP is an E3 ubiquitin ligase for mammalian thioredoxin
GOA
curator
UniProt
UniProt protein ID
P10599
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10599
determination method
IPI
retrieved
8 April 2019
stated in
Thioredoxin nuclear translocation and interaction with redox factor-1 activates the activator protein-1 transcription factor in response to ionizing radiation
GOA
curator
UniProt
UniProt protein ID
P10599
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10599
determination method
IPI
retrieved
8 April 2019
stated in
Phosphotyrosine signaling networks in epidermal growth factor receptor overexpressing squamous carcinoma cells
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10599
determination method
IPI
retrieved
8 April 2019
stated in
Positive regulation of apoptosis signal-regulating kinase 1 signaling by ZPR9 protein, a zinc finger protein
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10599
determination method
IPI
retrieved
8 April 2019
stated in
Salmonella type III secretion effector SlrP is an E3 ubiquitin ligase for mammalian thioredoxin
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10599
determination method
IPI
retrieved
8 April 2019
stated in
A possible interaction of thioredoxin with VDUP1 in HeLa cells detected in a yeast two-hybrid system
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10599
determination method
IPI
retrieved
8 April 2019
stated in
The mammalian-membrane two-hybrid assay (MaMTH) for probing membrane-protein interactions in human cells
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10599
determination method
IPI
retrieved
8 April 2019
stated in
Thioredoxin modulates activator protein 1 (AP-1) activity and p27Kip1 degradation through direct interaction with Jab1
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10599
determination method
IPI
retrieved
8 April 2019
stated in
CIB1 functions as a Ca(2+)-sensitive modulator of stress-induced signaling by targeting ASK1
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10599
determination method
IPI
retrieved
8 April 2019
stated in
Toward an understanding of the protein interaction network of the human liver
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10599
determination method
IPI
retrieved
8 April 2019
stated in
Thioredoxin is required for S-nitrosation of procaspase-3 and the inhibition of apoptosis in Jurkat cells.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10599
determination method
IPI
retrieved
8 April 2019
stated in
Selective redox regulation of cytokine receptor signaling by extracellular thioredoxin-1.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10599
determination method
IPI
retrieved
8 April 2019
stated in
Regulation of epidermal growth factor receptor trafficking by lysine deacetylase HDAC6
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10599
determination method
IPI
retrieved
8 April 2019
stated in
Reactivation of oxidized PTP1B and PTEN by thioredoxin 1
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10599
determination method
IPI
retrieved
8 April 2019
stated in
Peroxiredoxin-2 and STAT3 form a redox relay for H2O2 signaling.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10599
determination method
IPI
retrieved
8 April 2019
stated in
Salmonella type III secretion effector SlrP is an E3 ubiquitin ligase for mammalian thioredoxin
GOA
curator
AgBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10599
determination method
IPI
cell component
biological process
Gene Atlas image
PBB GE TXN 208864 s at fs.png
732 × 530; 12 KB
0 references
Commons category
Thioredoxin
0 references

Identifiers

ChEBI ID
15033
0 references
DrugBank ID
11298
1 reference
stated in
DrugBank
DrugBank ID
11298
retrieved
6 July 2021
quotation
CAS no.: 52500-60-4 (English)
title
Thioredoxin (English)
PDB structure ID
 
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