(Q4236472)

http://www.ebi.ac.uk/interpro/protein/P23528

Cofilin 1

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P23528

Actin-depolymerising factor homology domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

12 references

8 April 2019

HUNK suppresses metastasis of basal type breast cancers by disrupting the interaction between PP2A and cofilin-1.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23528

8 April 2019

New host factors important for respiratory syncytial virus (RSV) replication revealed by a novel microfluidics screen for interactors of matrix (M) protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23528

8 April 2019

A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23528

8 April 2019

Direct stimulation of receptor-controlled phospholipase D1 by phospho-cofilin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23528

8 April 2019

Phosphorylation of Ser 402 impedes phosphatase activity of slingshot 1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23528

8 April 2019

Regulation of actin function by protein kinase A-mediated phosphorylation of Limk1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23528

8 April 2019

Towards a proteome-scale map of the human protein–protein interaction network

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23528

8 April 2019

A proteome-scale map of the human interactome network

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23528

8 April 2019

Comprehensive proteomic analysis of interphase and mitotic 14-3-3-binding proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23528

8 April 2019

14-3-3 regulates actin dynamics by stabilizing phosphorylated cofilin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23528

8 April 2019

New host factors important for respiratory syncytial virus (RSV) replication revealed by a novel microfluidics screen for interactors of matrix (M) protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23528

8 April 2019

Proteomic profiling of cellular proteins interacting with the hepatitis C virus core protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23528

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23528

IPI

actin filament binding

3 references

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23528

8 April 2019

Determining the differences in actin binding by human ADF and cofilin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23528

signaling receptor binding

IDA

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23528

4 references

8 April 2019

Proteomics of human umbilical vein endothelial cells applied to etoposide-induced apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23528

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23528

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23528

8 April 2019

New host factors important for respiratory syncytial virus (RSV) replication revealed by a novel microfluidics screen for interactors of matrix (M) protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23528

1 reference

18 July 2017

Characterization of exosome-like vesicles released from human tracheobronchial ciliated epithelium: a possible role in innate defense

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P23528

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23528

2 references

1 reference

18 July 2017

Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P23528

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23528

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23528

intracellular anatomical structure

1 reference

18 July 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P23528

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23528

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23528

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23528

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23528

lamellipodium membrane

1 reference

8 April 2019

Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT)

extracellular exosome

4 references

18 July 2017

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P23528

18 July 2017

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P23528

18 July 2017

Proteomic analysis of podocyte exosome-enriched fraction from normal human urine

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P23528

18 July 2017

MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P23528

3 references

8 April 2019

Proteomics of human umbilical vein endothelial cells applied to etoposide-induced apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23528

8 April 2019

Characterization of a novel cofilin isoform that is predominantly expressed in mammalian skeletal muscle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23528

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23528

1 reference

18 July 2017

SILAC-based proteomics of human primary endothelial cell morphogenesis unveils tumor angiogenic markers

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=P23528

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23528

cortical actin cytoskeleton

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23528

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23528

1 reference

8 April 2019

Shotgun proteomics reveals specific modulated protein patterns in tears of patients with primary open angle glaucoma naïve to therapy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23528

1 reference

14 January 2019

Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P23528&geneProductId=UniProtKB:P23528

1 reference

8 April 2019

Characterization of exosome-like vesicles released from human tracheobronchial ciliated epithelium: a possible role in innate defense

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23528

Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT)

HDA

extracellular exosome

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23528

8 April 2019

MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23528

8 April 2019

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23528

1 reference

8 April 2019

Transcriptomic and proteomic analyses of rhabdomyosarcoma cells reveal differential cellular gene expression in response to enterovirus 71 infection

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23528

negative regulation of apoptotic process

IEP

1 reference

8 April 2019

Proteomics of human umbilical vein endothelial cells applied to etoposide-induced apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23528

positive regulation by host of viral process

1 reference

8 April 2019

New host factors important for respiratory syncytial virus (RSV) replication revealed by a novel microfluidics screen for interactors of matrix (M) protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23528

cytoskeleton organization

1 reference

8 April 2019

Identification and characterization of a set of conserved and new regulators of cytoskeletal organization, cell morphology and migration

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23528

Rho protein signal transduction

1 reference

8 April 2019

Signaling from Rho to the actin cytoskeleton through protein kinases ROCK and LIM-kinase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23528

regulation of cell morphogenesis

1 reference

8 April 2019

Identification and characterization of a set of conserved and new regulators of cytoskeletal organization, cell morphology and migration

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23528

regulation of dendritic spine morphogenesis

1 reference

8 April 2019

LRRK2 regulates synaptogenesis and dopamine receptor activation through modulation of PKA activity

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23528

actin cytoskeleton organization

1 reference

8 April 2019

Signaling from Rho to the actin cytoskeleton through protein kinases ROCK and LIM-kinase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23528

actin filament depolymerization

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23528

neural crest cell migration

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23528

neural fold formation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23528

protein phosphorylation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23528

actin filament organization

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23528

establishment of cell polarity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23528

actin filament fragmentation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23528

positive regulation of actin filament depolymerization

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23528

response to amino acid

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23528

interleukin-12-mediated signaling pathway

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23528

actin filament depolymerization

4 references

8 April 2019

Human LilrB2 is a β-amyloid receptor and its murine homolog PirB regulates synaptic plasticity in an Alzheimer's model

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23528

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23528

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23528

8 April 2019

Determining the differences in actin binding by human ADF and cofilin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P23528

Actin-depolymerising factor homology domain

IDA

Gene Atlas image

PBB GE CFL1 200021 at fs.png
732 × 530; 12 KB

0 references

has part(s)

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P23528

Identifiers

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016