Wikidata

(Q425812)

English

General transcription factor IIB

mammalian protein found in Homo sapiens

  • GTF2B
  • S300-II
  • RNA polymerase II transcription factor IIB
  • general transcription factor TFIIB
  • transcription initiation factor IIB
In more languages

Statements

molecular function
protein binding
determination method
IPI
19 references
retrieved
1 January 2018
stated in
Cloning and properties of the Caenorhabditis elegans TATA-box-binding protein
GOA
curator
WormBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00403
determination method
IPI
retrieved
1 January 2018
stated in
Structural basis of preinitiation complex assembly on human pol II promoters
GOA
curator
UniProt
UniProt protein ID
Q00403
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00403
determination method
IPI
retrieved
1 January 2018
stated in
Members of the steroid hormone receptor superfamily interact with TFIIB (S300-II)
GOA
curator
UniProt
UniProt protein ID
Q00403
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00403
determination method
IPI
retrieved
1 January 2018
stated in
Multiple functional domains of human transcription factor IIB: distinct interactions with two general transcription factors and RNA polymerase II.
GOA
curator
UniProt
UniProt protein ID
Q00403
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00403
determination method
IPI
retrieved
1 January 2018
stated in
Structural dissection of an interaction between transcription initiation and termination factors implicated in promoter-terminator cross-talk.
GOA
curator
UniProt
UniProt protein ID
Q00403
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00403
determination method
IPI
retrieved
1 January 2018
stated in
RNA polymerase II-associated protein (RAP) 74 binds transcription factor (TF) IIB and blocks TFIIB-RAP30 binding
GOA
curator
UniProt
UniProt protein ID
Q00403
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00403
determination method
IPI
retrieved
1 January 2018
stated in
Transcription factor IIB acetylates itself to regulate transcription
GOA
curator
UniProt
UniProt protein ID
Q00403
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00403
determination method
IPI
retrieved
1 January 2018
stated in
Characterization of Bcl10 as a potential transcriptional activator that interacts with general transcription factor TFIIB
GOA
curator
UniProt
UniProt protein ID
Q00403
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00403
determination method
IPI
retrieved
1 January 2018
stated in
The high mobility group protein HMG1 can reversibly inhibit class II gene transcription by interaction with the TATA-binding protein
GOA
curator
UniProt
UniProt protein ID
Q00403
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00403
determination method
IPI
retrieved
1 January 2018
stated in
The equine herpesvirus 1 EICP27 protein enhances gene expression via an interaction with TATA box-binding protein
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00403
determination method
IPI
retrieved
1 January 2018
stated in
A proteome-scale map of the human interactome network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00403
determination method
IPI
retrieved
1 January 2018
stated in
Specificity of cyclin E-Cdk2, TFIIB, and E1A interactions with a common domain of the p300 coactivator
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00403
determination method
IPI
retrieved
1 January 2018
stated in
Interaction of the equine herpesvirus 1 EICP0 protein with the immediate-early (IE) protein, TFIIB, and TBP may mediate the antagonism between the IE and EICP0 proteins
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00403
determination method
IPI
retrieved
1 January 2018
stated in
Specific interactions with TBP and TFIIB in vitro suggest that 14-3-3 proteins may participate in the regulation of transcription when part of a DNA binding complex
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00403
determination method
IPI
retrieved
1 January 2018
stated in
Interactions of SKIP/NCoA-62, TFIIB, and retinoid X receptor with vitamin D receptor helix H10 residues
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00403
determination method
IPI
retrieved
1 January 2018
stated in
Direct interaction of TFIIB and the IE protein of equine herpesvirus 1 is required for maximal trans-activation function
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00403
determination method
IPI
retrieved
1 January 2018
stated in
The high mobility group protein HMG1 can reversibly inhibit class II gene transcription by interaction with the TATA-binding protein
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00403
determination method
IPI
retrieved
1 January 2018
stated in
Interaction of the equine herpesvirus 1 EICP0 protein with the immediate-early (IE) protein, TFIIB, and TBP may mediate the antagonism between the IE and EICP0 proteins
GOA
curator
AgBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00403
determination method
IPI
retrieved
1 January 2018
stated in
Direct interaction of TFIIB and the IE protein of equine herpesvirus 1 is required for maximal trans-activation function
GOA
curator
AgBase
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00403
determination method
IPI
cell component
biological process
transcription by RNA polymerase II
determination method
IMP
TAS
9 references
retrieved
10 September 2018
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q00403&geneProductId=UniProtKB:Q00403
determination method
TAS
retrieved
10 September 2018
stated in
Solution structure of the C-terminal core domain of human TFIIB: similarity to cyclin A and interaction with TATA-binding protein
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q00403&geneProductId=UniProtKB:Q00403
determination method
TAS
retrieved
10 September 2018
stated in
Cloning of a human gene encoding the general transcription initiation factor IIB
GOA
curator
UniProt
UniProt protein ID
Q00403
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q00403&geneProductId=UniProtKB:Q00403
determination method
IMP
retrieved
10 September 2018
stated in
Recycling of the general transcription factors during RNA polymerase II transcription
GOA
curator
UniProt
UniProt protein ID
Q00403
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q00403&geneProductId=UniProtKB:Q00403
determination method
IMP
retrieved
10 September 2018
stated in
Members of the steroid hormone receptor superfamily interact with TFIIB (S300-II)
GOA
curator
UniProt
UniProt protein ID
Q00403
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q00403&geneProductId=UniProtKB:Q00403
determination method
IMP
retrieved
10 September 2018
stated in
A core promoter element downstream of the TATA box that is recognized by TFIIB.
GOA
curator
UniProt
UniProt protein ID
Q00403
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q00403&geneProductId=UniProtKB:Q00403
determination method
IMP
retrieved
10 September 2018
stated in
Functional dissection of TFIIB domains required for TFIIB-TFIID-promoter complex formation and basal transcription activity
GOA
curator
UniProt
UniProt protein ID
Q00403
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q00403&geneProductId=UniProtKB:Q00403
determination method
IMP
retrieved
10 September 2018
stated in
Potential RNA polymerase II-induced interactions of transcription factor TFIIB.
GOA
curator
UniProt
UniProt protein ID
Q00403
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q00403&geneProductId=UniProtKB:Q00403
determination method
IMP
retrieved
10 September 2018
stated in
Functional domains of transcription factor TFIIB.
GOA
curator
UniProt
UniProt protein ID
Q00403
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q00403&geneProductId=UniProtKB:Q00403
determination method
IMP
transcription by RNA polymerase II
determination method
IDA
IMP
TAS
10 references
retrieved
1 January 2018
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00403
determination method
TAS
retrieved
1 January 2018
stated in
Solution structure of the C-terminal core domain of human TFIIB: similarity to cyclin A and interaction with TATA-binding protein
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00403
determination method
TAS
retrieved
1 January 2018
stated in
Members of the steroid hormone receptor superfamily interact with TFIIB (S300-II)
GOA
curator
UniProt
UniProt protein ID
Q00403
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00403
determination method
IMP
retrieved
1 January 2018
stated in
A core promoter element downstream of the TATA box that is recognized by TFIIB.
GOA
curator
UniProt
UniProt protein ID
Q00403
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00403
determination method
IMP
retrieved
1 January 2018
stated in
Cloning of a human gene encoding the general transcription initiation factor IIB
GOA
curator
UniProt
UniProt protein ID
Q00403
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00403
determination method
IMP
retrieved
1 January 2018
stated in
Functional dissection of TFIIB domains required for TFIIB-TFIID-promoter complex formation and basal transcription activity
GOA
curator
UniProt
UniProt protein ID
Q00403
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00403
determination method
IMP
retrieved
1 January 2018
stated in
Recycling of the general transcription factors during RNA polymerase II transcription
GOA
curator
UniProt
UniProt protein ID
Q00403
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00403
determination method
IMP
retrieved
1 January 2018
stated in
Potential RNA polymerase II-induced interactions of transcription factor TFIIB.
GOA
curator
UniProt
UniProt protein ID
Q00403
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00403
determination method
IMP
retrieved
1 January 2018
stated in
Functional domains of transcription factor TFIIB.
GOA
curator
UniProt
UniProt protein ID
Q00403
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00403
determination method
IMP
retrieved
1 January 2018
stated in
Near-atomic resolution visualization of human transcription promoter opening
GOA
curator
ARUK-UCL
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q00403
determination method
IDA
Gene Atlas image
PBB GE GTF2B 208066 s at fs.png
732 × 530; 11 KB
0 references

Identifiers

PDB structure ID
 
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