(Q45314290)

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Signaling by ROBO receptors

An instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-376176)

Slit/ROBO pathway
SLIT-ROBO pathway

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8 July 2022

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https://identifiers.org/reactome:R-HSA-376176

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Regulation of expression of SLITs and ROBOs

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Regulation of commissural axon pathfinding by SLIT and ROBO

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Regulation of cortical dendrite branching

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8 July 2022

Inactivation of CDC42 and RAC1

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8 July 2022

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Role of ABL in ROBO-SLIT signaling

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SLIT2:ROBO1 increases RHOA activity

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ROBO receptors bind AKAP5

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Proteolytic processing of SLIT

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Glypican-1 (GPC1) binds SLIT2

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8 July 2022

SLITs bind keratan sulfate

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ROBOs bind keratan sulfate

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8 July 2022

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ROBO1,ROBO2 bind SLIT3

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Ena/VASP proteins bind ROBO1:SLIT2 complex

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8 July 2022

Recruitment of Profilin by Ena/VASP proteins

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SLIT2:ROBO1 binds CXCR4

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Slit/Robo signaling modulates the proliferation of central nervous system progenitors

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8 July 2022

Structural insight into Slit-Robo signalling

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8 July 2022

Operational redundancy in axon guidance through the multifunctional receptor Robo3 and its ligand NELL2.

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8 July 2022

Repulsive axon guidance molecule Slit3 is a novel angiogenic factor

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8 July 2022

Motor axon exit from the mammalian spinal cord is controlled by the homeodomain protein Nkx2.9 via Robo-Slit signaling

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8 July 2022

Roundabout receptors.

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Spontaneous activity regulates Robo1 transcription to mediate a switch in thalamocortical axon growth.

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8 July 2022

Identifiers

1 reference

8 July 2022

(Q45314290)

Signaling by ROBO receptors

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