(Q45314434)

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Hh mutants are degraded by ERAD

An instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-5362768)

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8 July 2022

Hh mutants abrogate ligand secretion

1 reference

8 July 2022

1 reference

8 July 2022

https://identifiers.org/reactome:R-HSA-5362768

1 reference

8 July 2022

HPE SHH variants don't undergo autoproteolytic cleavage

1 reference

8 July 2022

Hh processing variants bind lectins

1 reference

8 July 2022

Hh processing variants are recruited to SEL1:SYVN at the ER membrane

1 reference

8 July 2022

Hh processing variants are translocated to the cytosol in a VCP-dependent manner

1 reference

8 July 2022

processing defective Hh variants are degraded by the proteasome

1 reference

8 July 2022

Hh processing variants are ubiquitinated

1 reference

8 July 2022

A review of hedgehog signaling in cranial bone development

1 reference

8 July 2022

The molecular genetics of holoprosencephaly

1 reference

8 July 2022

The mutational spectrum of holoprosencephaly-associated changes within the SHH gene in humans predicts loss-of-function through either key structural alterations of the ligand or its altered synthesis

1 reference

8 July 2022

Identifiers

1 reference

8 July 2022

(Q45314434)

Hh mutants are degraded by ERAD

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