(Q45316601)

English

Tat-mediated elongation of the HIV-1 transcript

An instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-167246)

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8 July 2022

positive regulation of viral transcription

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8 July 2022

HIV Transcription Elongation

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8 July 2022

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8 July 2022

https://identifiers.org/reactome:R-HSA-167246

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8 July 2022

Formation of HIV-1 elongation complex containing HIV-1 Tat

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8 July 2022

Addition of nucleotides leads to HIV-1 transcript elongation

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8 July 2022

Pol II elongation complex moves on the HIV-1 template as transcript elongates

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8 July 2022

Separation of elongating HIV-1 transcript from template

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8 July 2022

Lentivirus Tat proteins specifically associate with a cellular protein kinase, TAK, that hyperphosphorylates the carboxyl-terminal domain of the large subunit of RNA polymerase II: candidate for a Tat cofactor

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8 July 2022

NELF, a multisubunit complex containing RD, cooperates with DSIF to repress RNA polymerase II elongation

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8 July 2022

HIV-1 infection and regulation of Tat function in macrophages

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8 July 2022

A novel CDK9-associated C-type cyclin interacts directly with HIV-1 Tat and mediates its high-affinity, loop-specific binding to TAR RNA

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8 July 2022

Domains in the SPT5 protein that modulate its transcriptional regulatory properties

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8 July 2022

Tat modifies the activity of CDK9 to phosphorylate serine 5 of the RNA polymerase II carboxyl-terminal domain during human immunodeficiency virus type 1 transcription

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8 July 2022

Tat transactivation: a model for the regulation of eukaryotic transcriptional elongation

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8 July 2022

Human immunodeficiency virus 1 tat protein binds trans-activation-responsive region (TAR) RNA in vitro

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8 July 2022

DSIF, a novel transcription elongation factor that regulates RNA polymerase II processivity, is composed of human Spt4 and Spt5 homologs

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8 July 2022

A new paradigm in eukaryotic biology: HIV Tat and the control of transcriptional elongation

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8 July 2022

Evidence that negative elongation factor represses transcription elongation through binding to a DRB sensitivity-inducing factor/RNA polymerase II complex and RNA.

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8 July 2022

Dynamics of human immunodeficiency virus transcription: P-TEFb phosphorylates RD and dissociates negative effectors from the transactivation response element

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8 July 2022

Anti-termination of transcription within the long terminal repeat of HIV-1 by tat gene product

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8 July 2022

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8 July 2022

Identifiers

1 reference

8 July 2022

(Q45316601)

Tat-mediated elongation of the HIV-1 transcript

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