(Q45316795)

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TFAP2 (AP-2) family regulates transcription of growth factors and their receptors

An instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-8866910)

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8 July 2022

regulation of transcription by RNA polymerase II

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Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors

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8 July 2022

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https://identifiers.org/reactome:R-HSA-8866910

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TFAP2A,TFAP2C homodimers bind ESR1 promoter

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TFAP2A,TFAP2C homodimers stimulate ESR1 gene expression

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TFAP2A,TFAP2C homodimers bind the CGA gene

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TFAP2A,TFAP2C homodimers stimulate CGA gene expression

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TFAP2A,TFAP2C homodimers bind the CGB gene promoter

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TFAP2A,TFAP2C homodimers stimulate CGB3 gene expression

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CGA and CGB3 bind to form Human chorionic gonadotropin (hCG)

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TFAP2A,(TFAP2B,TFAP2C) homo- and heterodimers bind the ERBB2 gene promoter and recruit YY1

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TFAP2A,(TFAP2B,TFAP2C) homo- and heterodimers and YY1 stimulate ERBB2 gene expression

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TFAP2A,(TFAP2B) homodimers bind the KIT gene promoter

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KIT gene expression is stimulated by TFAP2A,(TFAP2B) homodimers

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TFAP2A homodimer binds the VEGFA gene promoter

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VEGFA gene expression is inhibited by the TFAP2A homodimer

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TFAP2A homodimer binds the TGFA gene promoter

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TGFA gene expression is stimulated by the TFAP2A homodimer

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TFAP2C homodimer binds the EGFR gene promoter

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EGFR gene expression is stimulated by TFAP2C

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Transcriptional regulation of estrogen receptor in breast carcinomas

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AP2alpha and AP2gamma: a comparison of binding site specificity and trans-activation of the estrogen receptor promoter and single site promoter constructs.

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Yin Yang 1 cooperates with activator protein 2 to stimulate ERBB2 gene expression in mammary cancer cells

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EGFR Is Regulated by TFAP2C in Luminal Breast Cancer and Is a Target for Vandetanib.

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Regulation of the human chorionic gonadotropin alpha- and beta-subunit promoters by AP-2.

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CITED2 mutation links congenital heart defects to dysregulation of the cardiac gene VEGF and PITX2C expression

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AP-2 family members regulate basal and cAMP-induced expression of human chorionic gonadotropin

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Loss of AP-2 results in downregulation of c-KIT and enhancement of melanoma tumorigenicity and metastasis.

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Activator protein 2alpha inhibits tumorigenicity and represses vascular endothelial growth factor transcription in prostate cancer cells

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A family of AP-2 proteins regulates c-erbB-2 expression in mammary carcinoma

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Expression of AP-2 transcription factors in human breast cancer correlates with the regulation of multiple growth factor signalling pathways.

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Transcription factor AP-2 controls transcription of the human transforming growth factor-alpha gene

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8 July 2022

Identifiers

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8 July 2022

(Q45316795)

TFAP2 (AP-2) family regulates transcription of growth factors and their receptors

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