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JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
An instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-450321)
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Statements
instance of
biological pathway
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-450321
JNK cascade
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-450321
part of
MAP kinase activation
1 reference
stated in
Reactome
retrieved
13 July 2022
Reactome ID
R-HSA-450321
found in taxon
Homo sapiens
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-450321
exact match
https://identifiers.org/reactome:R-HSA-450321
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-450321
has part(s)
Phosphorylation of human JNKs by activated MKK4/MKK7
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-450321
Activated human JNKs migrate to nucleoplasm
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-450321
Activated TAK1 phosphorylates MKK4/MKK7
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-450321
cites work
IL-17 mediates inflammatory reactions via p38/c-Fos and JNK/c-Jun activation in an AP-1-dependent manner in human nucleus pulposus cells
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-450321
Simultaneous blockade of NFkappaB, JNK, and p38 MAPK by a kinase-inactive mutant of the protein kinase TAK1 sensitizes cells to apoptosis and affects a distinct spectrum of tumor necrosis factor [corrected] target genes
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-450321
TAK1 is a ubiquitin-dependent kinase of MKK and IKK
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-450321
Identifiers
Reactome ID
R-HSA-450321
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-450321
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