(Q45316991)

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activated TAK1 mediates p38 MAPK activation

An instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-450302)

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8 July 2022

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8 July 2022

MAP kinase activation

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13 July 2022

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8 July 2022

https://identifiers.org/reactome:R-HSA-450302

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8 July 2022

Phosphorylated MKK3/MKK6 migrates to nucleus

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8 July 2022

Activated human MKK3/MKK6 phosphorylates p38 MAPK complexed with MAPKAPK2 or MAPKAPK3

1 reference

8 July 2022

Active p38 MAPK phosphorylates MAPKAPK2 or 3

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8 July 2022

activated human TAK1 phosphorylates MKK3/MKK6

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8 July 2022

Nuclear export of human p38 MAPK mediated by its substrate MAPKAPK2 or 3

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8 July 2022

IL-17 mediates inflammatory reactions via p38/c-Fos and JNK/c-Jun activation in an AP-1-dependent manner in human nucleus pulposus cells

1 reference

8 July 2022

Simultaneous blockade of NFkappaB, JNK, and p38 MAPK by a kinase-inactive mutant of the protein kinase TAK1 sensitizes cells to apoptosis and affects a distinct spectrum of tumor necrosis factor [corrected] target genes

1 reference

8 July 2022

Identification of a member of the MAPKKK family as a potential mediator of TGF-beta signal transduction

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8 July 2022

Identifiers

1 reference

8 July 2022

(Q45316991)

activated TAK1 mediates p38 MAPK activation

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