(Q45317027)

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TRAF6-mediated induction of TAK1 complex within TLR4 complex

An instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-937072)

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1 reference

8 July 2022

I-kappaB kinase/NF-kappaB signaling

1 reference

8 July 2022

TRIF(TICAM1)-mediated TLR4 signaling

1 reference

8 July 2022

1 reference

8 July 2022

https://identifiers.org/reactome:R-HSA-937072

1 reference

8 July 2022

Activated TRAF6 synthesizes unanchored polyubiquitin chains upon TLR stimulation

1 reference

8 July 2022

Activated TLR4:TICAM1 recruits TRAF6

1 reference

8 July 2022

Auto ubiquitination of TRAF6 bound to the activated TLR4 complex

1 reference

8 July 2022

Activated TLR4:TICAM1:K63pUb-TRAF6 recruits TAK1complex

1 reference

8 July 2022

Activation of TAK1 complex bound to activated TLR4 complex

1 reference

8 July 2022

Phosphorylated TAK1 leaves activated TLR receptor complex

1 reference

8 July 2022

TRAF6 autoubiquitination-independent activation of the NFkappaB and MAPK pathways in response to IL-1 and RANKL

1 reference

8 July 2022

Direct activation of protein kinases by unanchored polyubiquitin chains

1 reference

8 July 2022

Identifiers

1 reference

8 July 2022

(Q45317027)

TRAF6-mediated induction of TAK1 complex within TLR4 complex

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