(Q45317077)

English

Regulation of actin dynamics for phagocytic cup formation

An instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-2029482)

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1 reference

8 July 2022

Fcgamma receptor (FCGR) dependent phagocytosis

1 reference

8 July 2022

1 reference

8 July 2022

https://identifiers.org/reactome:R-HSA-2029482

1 reference

8 July 2022

Dimerization of LIMK1 by Hsp90

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8 July 2022

Transphosphorylation of pLIMK1

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8 July 2022

Phosphorylation of cofilin by LIMK-1

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8 July 2022

Recruitment of VAV1 to p-6Y-SYK

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8 July 2022

Phosphorylation of VAV

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8 July 2022

Activation of RAC1 by VAV

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8 July 2022

Recruitment of CRKII:DOCK180:ELMO complex to FCGR

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8 July 2022

Activation of RAC1 by CRKII:DOCK180:ELMO

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8 July 2022

RAC1:GTP and PIP3 bind WAVE Regulatory Complex (WRC)

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8 July 2022

p-ERK phosphorylates WAVEs and ABI

1 reference

8 July 2022

ABL phosphorylates WAVEs

1 reference

8 July 2022

An unknown GEF exchanges GTP for GDP on CDC42:GDP

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8 July 2022

Activation of WASP and N-WASP by CDC42

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8 July 2022

WIP binds WASP,N-WASP, activating them

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8 July 2022

Src phosphorylate WASP,N-WASP

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8 July 2022

WASPs or WAVEs activate the ARP2/3 complex

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8 July 2022

(WASPs, WAVE):G-actin:ARP2/3 binds F-actin

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8 July 2022

Detachment of WASP/WAVE

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8 July 2022

Branching and elongation of mother and daughter filaments

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8 July 2022

RAC1 and CDC42 activate PAK1

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8 July 2022

Autophosphorylation of PAK1

1 reference

8 July 2022

PAK1 phosphorylates LIMK1

1 reference

8 July 2022

Extension of pseudopodia by myosin-X in a PI3K dependent manner

1 reference

8 July 2022

Role of myosins in phagosome formation

1 reference

8 July 2022

Regulation of actin filament assembly by Arp2/3 complex and formins

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8 July 2022

Regulation of WASP/WAVE proteins: making a long story short

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8 July 2022

Regulation of phagocytosis by Rho GTPases

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8 July 2022

Identifiers

1 reference

8 July 2022

(Q45317077)

Regulation of actin dynamics for phagocytic cup formation

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