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Alpha-defensins
An instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-1462054)
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Statements
instance of
biological pathway
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-1462054
part of
Defensins
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-1462054
found in taxon
Homo sapiens
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-1462054
exact match
https://identifiers.org/reactome:R-HSA-1462054
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-1462054
has part(s)
Pro-HNP1-4 are cleaved to biologically active defensin
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-1462054
HNP1-4 are stored in primary neutrophil granules
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-1462054
HNP1-4 are released into phagocytic vacuoles
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-1462054
pro-defensin alpha 5 is stored in Paneth cell granules
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-1462054
pro-defensin alpha 5 is secreted
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-1462054
pro-HD5 is cleaved by trypsin
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-1462054
Alpha-defensins form biologically active dimers
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-1462054
Alpha-defensin dimers adsorb onto microbial membrane anionic phospholipids
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-1462054
Alpha-defensin dimers multimerize to form a pore complex
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-1462054
HNP1-3 bind gp120
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-1462054
HNP1-3 bind CD4
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-1462054
ADP-Ribosylation of HNP-1
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-1462054
cites work
Defensins: antimicrobial peptides of innate immunity
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-1462054
Identifiers
Reactome ID
R-HSA-1462054
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-1462054
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