(Q45317421)

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Retinoid metabolism and transport

An instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-975634)

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8 July 2022

retinoid metabolic process

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Metabolism of fat-soluble vitamins

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Visual phototransduction

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https://identifiers.org/reactome:R-HSA-975634

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PNLIP:CLPS hydrolyses RPALM to atROL and PALM

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PLB1 hydrolyses RPALM to atROL

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BCMO1:Fe2+ cleaves betaC to atRAL

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BCO2:Fe2+ cleaves betaC to APO10al and bION

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RDH11 reduces RBP2:atRAL to RBP2:atROL

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AKRs reduce RBP2:atRAL to RBP2:atROL

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LRAT esterifies RBP2:atROL and FACYLs to atREs

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atREs binds to nascent CM

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Cytosolic CMs translocate to extracellular region

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Nascent CMs transform into mature CMs

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LPL hydrolyses TGs from mature CMs

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LDLR transports extracellular CR:atREs to cytosol

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CR:atREs binds apoE and HSPG

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LRPs transport extracellular CR:atREs:HSPG:apoE to cytosol

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NREH hydrolyses atREs to atROL and FAs

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NREH hydrolyses atREs (HSPG:apoE) to atROL and FAs

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RETSAT reduces atROL to at-13,14-dhROL

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Parenchymal atROL translocates to HSCs

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atROL binds RBP1 (parenchymal cell)

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A REH hydrolses atREs to atROL and FAs

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LRAT esterifies RBP1:atROL and FACYLs to atREs

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HSC cytosolic atROL translocates to extracellular region

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Mechanisms of digestion and absorption of dietary vitamin A.

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Mechanisms involved in the intestinal digestion and absorption of dietary vitamin A

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8 July 2022

Identifiers

1 reference

8 July 2022

(Q45317421)

Retinoid metabolism and transport

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