(Q45317722)

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Metabolism of Angiotensinogen to Angiotensins

An instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-2022377)

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angiotensin maturation

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Peptide hormone metabolism

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https://identifiers.org/reactome:R-HSA-2022377

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Renin hydrolyzes Angiotensinogen to Angiotensin-(1-10)

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Renin:Prorenin Receptor hydrolyzes Angiotensinogen to Angiotensin-(1-10)

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Prorenin:Prorenin Receptor hydrolyzes Angiotensinogen to Angiotensin-(1-10)

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ACE hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8)

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Secreted ACE hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8)

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Chymase hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8)

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Cathepsin G hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8)

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Cathepsin Z (Cathepsin X) hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-8)

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ACE2 hydrolyzes Angiotensin-(1-10) to Angiotensin-(1-9)

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ACE hydrolyzes Angiotensin-(1-9) to Angiotensin-(1-7)

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MME:Zn2+ hydrolyses AGT(34-42)

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MME:Zn2+ hydrolyses AGT(34-43)

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ENPEP hydrolyzes Angiotensin-(1-8) to Angiotensin-(2-8)

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ANPEP hydrolyzes Angiotensin-(2-8) to Angiotensin-(3-8)

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ACE2 hydrolyzes Angiotensin-(1-8) to Angiotensin-(1-7)

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Mast Cell Carboxypeptidase hydrolyzes Angiotensin-(1-10) to Yield Angiotensin-(1-9)

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AOPEP:Zn2+ hydrolyses AGT(35-41) to AGT(36-41)

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CES1trimer hydrolyses ACEI pro-drugs to ACEIs

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ACEIs translocate from ER lumen to extracellular region

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Recent advances involving the renin-angiotensin system

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The intracellular renin-angiotensin system: a new paradigm

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Aliskiren versus ramipril in hypertension

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Alternative pathways for angiotensin II generation in the cardiovascular system

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8 July 2022

A new look at the renin-angiotensin system--focusing on the vascular system

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The renin-angiotensin and the kallikrein-kinin systems

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Molecular and Pathophysiological Features of Angiotensinogen: A Mini Review

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8 July 2022

Renin-angiotensin system revisited

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8 July 2022

The physiological significance of the alternative pathways of angiotensin II production

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8 July 2022

Renin and cardiovascular disease: Worn-out path, or new direction

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8 July 2022

Is aliskiren superior to inhibitors of angiotensin-converting enzyme and angiotensin receptor blockers in renin-angiotensin system blockade?

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8 July 2022

Identifiers

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8 July 2022

(Q45317722)

Metabolism of Angiotensinogen to Angiotensins

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