(Q45318180)

English

G alpha (i) signalling events

An instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-418594)

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8 July 2022

GPCR downstream signalling

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8 July 2022

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8 July 2022

https://identifiers.org/reactome:R-HSA-418594

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8 July 2022

G alpha (i) inhibits adenylate cyclase

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8 July 2022

Adenylate cyclase converts ATP to 3',5'-cyclic AMP (cAMP) and pyrophosphate

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8 July 2022

Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi

1 reference

8 July 2022

Liganded Gi-activating GPCR acts as a GEF for Gi

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8 July 2022

The Ligand:GPCR:Gi complex dissociates

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8 July 2022

Opsins act as GEFs for G alpha-t

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8 July 2022

G alpha (i) auto-inactivates by hydrolysing GTP to GDP

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8 July 2022

Inactive G alpha (i) reassociates with G beta:gamma

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8 July 2022

Opsins binds G alpha-t

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8 July 2022

G-alpha(t):G-beta-gamma:Opsins complex dissociates to active G-alpha(t)

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8 July 2022

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8 July 2022

G alpha (i):GTP binds SRC

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8 July 2022

G protein alpha (i)-SRC complex catalyzes SRC to p-Y416-SRC

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8 July 2022

G protein alpha (i)-SRC complex dissociates to G protein alpha (i) and Active SRC

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8 July 2022

Active G alpha (i)–i1/i2/i3 binds RGS proteins

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8 July 2022

G alpha (i)–i1/i2/i3 in G (i):RGS complex is inactivated

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8 July 2022

G alpha (i):RGS dissociates to inactive G alpha (i)–i1/i2/i3

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8 July 2022

G proteins: transducers of receptor-generated signals

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8 July 2022

Role of subunit diversity in signaling by heterotrimeric G proteins

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8 July 2022

Identifiers

1 reference

8 July 2022

(Q45318180)

G alpha (i) signalling events

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