(Q45318181)

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G alpha (z) signalling events

An instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-418597)

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1 reference

8 July 2022

GPCR downstream signalling

1 reference

8 July 2022

1 reference

8 July 2022

https://identifiers.org/reactome:R-HSA-418597

1 reference

8 July 2022

Adenylate cyclase converts ATP to 3',5'-cyclic AMP (cAMP) and pyrophosphate

1 reference

8 July 2022

Liganded Gz-activating GPCRs bind inactive heterotrimeric G-protein Gz

1 reference

8 July 2022

Liganded Gz-activating GPCR acts as a GEF for Gz

1 reference

8 July 2022

The Ligand:GPCR:Gz complex dissociates

1 reference

8 July 2022

G alpha (z) inhibits adenylate cyclase

1 reference

8 July 2022

PKC phosphorylates G alpha (z)

1 reference

8 July 2022

G alpha (z) auto-inactivates by hydrolysing GTP to GDP

1 reference

8 July 2022

Inactive G alpha (z) reassociates with G beta:gamma

1 reference

8 July 2022

PKC binds active G alpha (z)

1 reference

8 July 2022

G-alpha(z):PKC dissociates to give phosphorylated G alpha (z)

1 reference

8 July 2022

Active G alpha (z) binds RGS proteins

1 reference

8 July 2022

G alpha (z) in G alpha (z):RGS complex is inactivated

1 reference

8 July 2022

G alpha (z):RGS complex dissociates to give inactive G alpha (z)

1 reference

8 July 2022

Identification of Gz alpha as a pertussis toxin-insensitive G protein in human platelets and megakaryocytes

1 reference

8 July 2022

G(z) signaling: emerging divergence from G(i) signaling

1 reference

8 July 2022

Identifiers

1 reference

8 July 2022

(Q45318181)

G alpha (z) signalling events

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