(Q45318396)

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Vasopressin regulates renal water homeostasis via Aquaporins

An instance of the biological pathway in Homo sapiens with Reactome ID (R-HSA-432040)

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8 July 2022

renal water homeostasis

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8 July 2022

Aquaporin-mediated transport

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8 July 2022

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8 July 2022

https://identifiers.org/reactome:R-HSA-432040

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Heterotrimeric G(s) complex dissociates

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8 July 2022

G alpha (s) activates adenylate cyclase

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8 July 2022

Activated Adenylate cyclase catalyses cAMP synthesis

1 reference

8 July 2022

cAMP induces dissociation of inactive PKA tetramers

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8 July 2022

AVP(20-28) binds AVPR2

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8 July 2022

AVP:AVPR2 Complex binds inactive heterotrimeric G(s) complex

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AVP:AVPR2:heterotrimeric G(s) complex exchanges GDP for GTP

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Phosphorylation of Aquaporin-2 by Protein Kinase A (PKA)

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Translocation of Aquaporin-2 from intracellular vesicles to the apical plasma membrane

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Aquaporin-1 passively transports water into cell

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p-S256-Aquaporin-2 passively transports water into cell

1 reference

8 July 2022

Aquaporin-1 passively transports water out of cell

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8 July 2022

Aquaporin-3 passively transports water out of cell

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8 July 2022

Aquaporin-4 passively transports water out of cell

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8 July 2022

cAMP binds PKA tetramer

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8 July 2022

The renal plumbing system: aquaporin water channels

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8 July 2022

Regulation of aquaporin-2 trafficking.

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8 July 2022

Regulation and dysregulation of aquaporins in water balance disorders

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8 July 2022

Aquaporins in the kidney: from molecules to medicine

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8 July 2022

Localization and trafficking of aquaporin 2 in the kidney.

1 reference

8 July 2022

Identifiers

1 reference

8 July 2022

(Q45318396)

Vasopressin regulates renal water homeostasis via Aquaporins

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