(Q4763281)

English

Angiomotin

mammalian protein found in Homo sapiens

angiomotin
angiomotin p80 isoform
angiomotin p130 isoform
AMOT

In more languages

Statements

1 reference

13 November 2019

UniProt protein ID

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q4VCS5

Angiomotin, C-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

protein binding

determination method

8 references

8 April 2019

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q4VCS5

determination method

8 April 2019

A tight junction-associated Merlin-angiomotin complex mediates Merlin's regulation of mitogenic signaling and tumor suppressive functions

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q4VCS5

determination method

8 April 2019

Merlin/NF2 loss-driven tumorigenesis linked to CRL4(DCAF1)-mediated inhibition of the hippo pathway kinases Lats1 and 2 in the nucleus

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q4VCS5

determination method

8 April 2019

Defining the human deubiquitinating enzyme interaction landscape

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q4VCS5

determination method

8 April 2019

A protein-protein interaction map of the TNF-induced NF-κB signal transduction pathway

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q4VCS5

determination method

8 April 2019

Interaction proteome of human Hippo signaling: modular control of the co-activator YAP1

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q4VCS5

determination method

8 April 2019

Angiomotin: an angiostatin binding protein that regulates endothelial cell migration and tube formation

HUGO Gene Nomenclature Committee

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q4VCS5

determination method

8 April 2019

New host factors important for respiratory syncytial virus (RSV) replication revealed by a novel microfluidics screen for interactors of matrix (M) protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q4VCS5

determination method

angiostatin binding

determination method

1 reference

8 April 2019

Angiomotin: an angiostatin binding protein that regulates endothelial cell migration and tube formation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q4VCS5

determination method

identical protein binding

determination method

1 reference

27 March 2018

A proteome-scale map of the human interactome network

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q4VCS5&geneProductId=UniProtKB:Q4VCS5

determination method

signaling receptor activity

determination method

1 reference

27 March 2018

Angiomotin: an angiostatin binding protein that regulates endothelial cell migration and tube formation

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q4VCS5&geneProductId=UniProtKB:Q4VCS5

determination method

determination method

1 reference

27 March 2018

Angiomotin regulates endothelial cell-cell junctions and cell motility

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q4VCS5&geneProductId=UniProtKB:Q4VCS5

determination method

integral component of membrane

determination method

1 reference

27 March 2018

Angiomotin regulates endothelial cell-cell junctions and cell motility

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q4VCS5&geneProductId=UniProtKB:Q4VCS5

determination method

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q4VCS5

determination method

determination method

1 reference

8 April 2019

Angiomotin: an angiostatin binding protein that regulates endothelial cell migration and tube formation

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q4VCS5

determination method

endocytic vesicle

determination method

1 reference

8 April 2019

Angiomotin: an angiostatin binding protein that regulates endothelial cell migration and tube formation

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q4VCS5

determination method

determination method

1 reference

27 March 2018

Angiomotin regulates endothelial cell-cell junctions and cell motility

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q4VCS5&geneProductId=UniProtKB:Q4VCS5

determination method

determination method

1 reference

27 March 2018

Angiomotin regulates endothelial cell-cell junctions and cell motility

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q4VCS5&geneProductId=UniProtKB:Q4VCS5

determination method

determination method

1 reference

8 April 2019

Angiomotin: an angiostatin binding protein that regulates endothelial cell migration and tube formation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q4VCS5

determination method

COP9 signalosome

determination method

1 reference

8 April 2019

Characterization of the human COP9 signalosome complex using affinity purification and mass spectrometry

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q4VCS5

determination method

cytoplasmic vesicle

determination method

1 reference

27 March 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q4VCS5&geneProductId=UniProtKB:Q4VCS5

determination method

external side of plasma membrane

determination method

1 reference

8 April 2019

Angiomotin: an angiostatin binding protein that regulates endothelial cell migration and tube formation

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q4VCS5

determination method

determination method

3 references

27 March 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q4VCS5&geneProductId=UniProtKB:Q4VCS5

determination method

27 March 2018

Angiomotin: an angiostatin binding protein that regulates endothelial cell migration and tube formation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q4VCS5&geneProductId=UniProtKB:Q4VCS5

determination method

27 March 2018

Angiomotin: an angiostatin binding protein that regulates endothelial cell migration and tube formation

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q4VCS5&geneProductId=UniProtKB:Q4VCS5

determination method

bicellular tight junction

determination method

3 references

27 March 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q4VCS5&geneProductId=UniProtKB:Q4VCS5

determination method

27 March 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q4VCS5&geneProductId=UniProtKB:Q4VCS5

determination method

27 March 2018

Angiomotin regulates endothelial cell-cell junctions and cell motility

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q4VCS5&geneProductId=UniProtKB:Q4VCS5

determination method

determination method

1 reference

8 April 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q4VCS5

determination method

bicellular tight junction

determination method

3 references

determination method

4 references

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q4VCS5

determination method

8 April 2019

Angiomotin: an angiostatin binding protein that regulates endothelial cell migration and tube formation

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q4VCS5

determination method

8 April 2019

Angiomotin: an angiostatin binding protein that regulates endothelial cell migration and tube formation

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q4VCS5

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q4VCS5

determination method

biological process

regulation of cell migration

determination method

1 reference

27 March 2018

Angiomotin: an angiostatin binding protein that regulates endothelial cell migration and tube formation

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q4VCS5&geneProductId=UniProtKB:Q4VCS5

determination method

blood vessel morphogenesis

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q4VCS5

determination method

blood vessel endothelial cell migration

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q4VCS5

determination method

gastrulation with mouth forming second

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q4VCS5

determination method

in utero embryonic development

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q4VCS5

determination method

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q4VCS5

determination method

establishment of cell polarity involved in ameboidal cell migration

determination method

1 reference

27 March 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q4VCS5&geneProductId=UniProtKB:Q4VCS5

determination method

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q4VCS5

determination method

negative regulation of GTPase activity

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q4VCS5

determination method

positive regulation of blood vessel endothelial cell migration

determination method

1 reference

27 March 2018

Angiomotin regulates endothelial cell-cell junctions and cell motility

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q4VCS5&geneProductId=UniProtKB:Q4VCS5

determination method

cell-cell junction assembly

determination method

1 reference

27 March 2018

Angiomotin regulates endothelial cell-cell junctions and cell motility

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q4VCS5&geneProductId=UniProtKB:Q4VCS5

determination method

positive regulation of cell size

determination method

1 reference

27 March 2018

Angiomotin regulates endothelial cell-cell junctions and cell motility

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q4VCS5&geneProductId=UniProtKB:Q4VCS5

determination method

negative regulation of angiogenesis

determination method

1 reference

8 April 2019

Angiomotin: an angiostatin binding protein that regulates endothelial cell migration and tube formation

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q4VCS5

determination method

cell migration involved in gastrulation

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q4VCS5

determination method

positive regulation of embryonic development

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q4VCS5

determination method

regulation of small GTPase mediated signal transduction

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q4VCS5

determination method

positive regulation of stress fiber assembly

determination method

1 reference

27 March 2018

Angiomotin regulates endothelial cell-cell junctions and cell motility

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q4VCS5&geneProductId=UniProtKB:Q4VCS5

determination method

negative regulation of vascular permeability

determination method

1 reference

27 March 2018

Angiomotin regulates endothelial cell-cell junctions and cell motility

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q4VCS5&geneProductId=UniProtKB:Q4VCS5

determination method

actin cytoskeleton organization

determination method

3 references

8 April 2019

Angiomotin regulates endothelial cell-cell junctions and cell motility

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q4VCS5

determination method

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q4VCS5

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q4VCS5

determination method

hippo signaling

determination method

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q4VCS5

determination method

8 April 2019

Angiomotin is a novel Hippo pathway component that inhibits YAP oncoprotein

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q4VCS5

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q4VCS5

determination method

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q4VCS5

determination method

Gene Atlas image

PBB GE AMOT 209521 s at fs.png
732 × 530; 12 KB

0 references

Angiomotin, C-terminal

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q4VCS5

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000305557

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000305557

ENSP00000361027

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000361027

ENSP00000429013

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000429013

ENSP00000361026

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000361026

ENSP00000361030

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000361030

Sitelinks

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