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Growth differentiation factor 9
mammalian protein found in Homo sapiens
GDF9
GDF-9B
growth differentiation factor 9
Growth/differentiation factor 9B
growth/differentiation factor 9
In more languages
default for all languages
No label defined
No description defined
edit
Statements
instance of
protein
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
O60383
part of
Cystine-knot cytokine
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/O60383
Growth differentiation factor-9
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/O60383
Transforming growth factor-beta, C-terminal domain, protein family
1 reference
based on heuristic
inferred from protein domain or family
Transforming growth factor beta, conserved site, protein family
1 reference
based on heuristic
inferred from protein domain or family
found in taxon
Homo sapiens
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
O60383
encoded by
GDF9
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
O60383
molecular function
transforming growth factor beta receptor binding
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60383
determination method
IBA
cytokine activity
determination method
IBA
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
O60383
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60383
determination method
IEA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60383
determination method
IBA
growth factor activity
determination method
IEA
TAS
3 references
retrieved
8 April 2019
stated in
Growth differentiation factor-9 is required during early ovarian folliculogenesis
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60383
determination method
TAS
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
O60383
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60383
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60383
determination method
IEA
cell component
cytoplasm
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60383
determination method
IEA
extracellular region
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
O60383
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60383
determination method
IEA
extracellular space
determination method
IBA
IEA
2 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
O60383
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60383
determination method
IEA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60383
determination method
IBA
biological process
regulation of apoptotic process
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60383
determination method
IBA
positive regulation of pathway-restricted SMAD protein phosphorylation
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60383
determination method
IBA
oocyte growth
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60383
determination method
IEA
regulation of MAPK cascade
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60383
determination method
IBA
transforming growth factor beta receptor signaling pathway
determination method
TAS
1 reference
retrieved
8 April 2019
stated in
Oocyte-specific expression of growth/differentiation factor-9
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60383
determination method
TAS
SMAD protein signal transduction
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60383
determination method
IBA
female gamete generation
determination method
TAS
2 references
retrieved
8 April 2019
stated in
Growth differentiation factor-9 is required during early ovarian folliculogenesis
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60383
determination method
TAS
retrieved
8 April 2019
stated in
Oocyte-specific expression of growth/differentiation factor-9
GOA
curator
Proteome Inc.
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60383
determination method
TAS
negative regulation of cell growth
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60383
determination method
IEA
BMP signaling pathway
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60383
determination method
IBA
cell development
determination method
IBA
1 reference
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60383
determination method
IBA
positive regulation of cell population proliferation
determination method
IDA
1 reference
retrieved
8 April 2019
stated in
Effects of growth differentiation factor 9 on cell cycle regulators and ERK42/44 in human granulosa cell proliferation
GOA
curator
UniProt
UniProt protein ID
O60383
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60383
determination method
IDA
regulation of progesterone secretion
determination method
IDA
IMP
2 references
retrieved
8 April 2019
stated in
Growth differentiation factor 9 reverses activin A suppression of steroidogenic acute regulatory protein expression and progesterone production in human granulosa-lutein cells
GOA
curator
UniProt
UniProt protein ID
O60383
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60383
determination method
IMP
retrieved
8 April 2019
stated in
Growth differentiation factor-9 inhibits 3'5'-adenosine monophosphate-stimulated steroidogenesis in human granulosa and theca cells
GOA
curator
UniProt
UniProt protein ID
O60383
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60383
determination method
IDA
regulation of signaling receptor activity
determination method
IEA
1 reference
retrieved
8 April 2019
stated in
GOA
curator
Gene Ontology Consortium
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O60383
determination method
IEA
Gene Atlas image
PBB GE GDF9 221314 at fs.png
732 × 530; 12 KB
0 references
exact match
http://purl.uniprot.org/uniprot/O60383
1 reference
stated in
Identifiers.org
has part(s)
Transforming growth factor-beta, C-terminal
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/O60383
Transforming growth factor beta, conserved site
1 reference
stated in
InterPro Release 71.0
reference URL
http://www.ebi.ac.uk/interpro/protein/O60383
Identifiers
RefSeq protein ID
NP_001275753
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
2661
NP_001275754
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
2661
NP_001275755
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
2661
NP_001275756
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
2661
NP_001275757
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
2661
NP_005251
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
2661
XP_005272014
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
2661
XP_006714648
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
2661
XP_011541610
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
2661
XP_011541611
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
2661
XP_011541612
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
2661
XP_011541613
1 reference
stated in
NCBI Gene
retrieved
30 May 2020
Entrez Gene ID
2661
UniProt protein ID
O60383
1 reference
stated in
UniProt
retrieved
13 November 2019
UniProt protein ID
O60383
Ensembl protein ID
ENSP00000367942
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000367942
ENSP00000296875
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000296875
ENSP00000484339
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000484339
ENSP00000485037
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000485037
ENSP00000485231
1 reference
stated in
Ensembl Release 99
Ensembl protein ID
ENSP00000485231
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