(Q5008266)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P21730

GPCR, rhodopsin-like, 7TM, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

complement component C5a binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21730

signal transducer activity

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P21730&geneProductId=UniProtKB:P21730

complement receptor activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21730

complement component C5a receptor activity

5 references

24 April 2018

rC5a directs the in vitro migration of human memory and naive tonsillar B lymphocytes: implications for B cell trafficking in secondary lymphoid tissues

http://www.ebi.ac.uk/QuickGO/annotations?protein=P21730&geneProductId=UniProtKB:P21730

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P21730&geneProductId=UniProtKB:P21730

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P21730&geneProductId=UniProtKB:P21730

24 April 2018

Human colonic epithelial cells detect and respond to C5a via apically expressed C5aR through the ERK pathway

http://www.ebi.ac.uk/QuickGO/annotations?protein=P21730&geneProductId=UniProtKB:P21730

24 April 2018

Cloning and characterization of a rabbit ortholog of human Galpha16 and mouse G(alpha)15

http://www.ebi.ac.uk/QuickGO/annotations?protein=P21730&geneProductId=UniProtKB:P21730

G protein-coupled receptor activity

4 references

8 April 2019

Cloning and characterization of a rabbit ortholog of human Galpha16 and mouse G(alpha)15

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21730

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21730

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21730

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21730

complement component C5a receptor activity

6 references

8 April 2019

rC5a directs the in vitro migration of human memory and naive tonsillar B lymphocytes: implications for B cell trafficking in secondary lymphoid tissues

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21730

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21730

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21730

8 April 2019

Cloning and characterization of a rabbit ortholog of human Galpha16 and mouse G(alpha)15

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21730

8 April 2019

Human colonic epithelial cells detect and respond to C5a via apically expressed C5aR through the ERK pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21730

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21730

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21730

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21730

8 April 2019

Expression cloning of a receptor for C5a anaphylatoxin on differentiated HL-60 cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21730

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21730

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21730

1 reference

8 April 2019

Human colonic epithelial cells detect and respond to C5a via apically expressed C5aR through the ERK pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21730

integral component of plasma membrane

1 reference

8 April 2019

Expression cloning of a receptor for C5a anaphylatoxin on differentiated HL-60 cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21730

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21730

basolateral plasma membrane

1 reference

8 April 2019

Novel insights in localization and expression levels of C5aR and C5L2 under native and post-transplant conditions in the kidney

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21730

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21730

secretory granule membrane

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21730

negative regulation of neuron apoptotic process

biological process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21730

positive regulation of epithelial cell proliferation

1 reference

8 April 2019

Human colonic epithelial cells detect and respond to C5a via apically expressed C5aR through the ERK pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21730

mRNA transcription by RNA polymerase II

1 reference

8 April 2019

Human colonic epithelial cells detect and respond to C5a via apically expressed C5aR through the ERK pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21730

activation of phospholipase C activity

1 reference

8 April 2019

Mitogen-activated protein kinase activation requires two signal inputs from the human anaphylatoxin C5a receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21730

neutrophil chemotaxis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21730

positive regulation of angiogenesis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21730

3 references

8 April 2019

rC5a directs the in vitro migration of human memory and naive tonsillar B lymphocytes: implications for B cell trafficking in secondary lymphoid tissues

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21730

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21730

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21730

cellular defense response

1 reference

8 April 2019

The C5a chemoattractant receptor mediates mucosal defence to infection

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21730

response to lipopolysaccharide

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21730

animal organ regeneration

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21730

1 reference

8 April 2019

Expression of receptors for C5a anaphylatoxin (CD88) on human bronchial epithelial cells: enhancement of C5a-mediated release of IL-8 upon exposure to cigarette smoke

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21730

response to peptidoglycan

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21730

positive regulation of ERK1 and ERK2 cascade

1 reference

8 April 2019

Human colonic epithelial cells detect and respond to C5a via apically expressed C5aR through the ERK pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21730

positive regulation of neutrophil chemotaxis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21730

complement receptor mediated signaling pathway

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P21730&geneProductId=UniProtKB:P21730

sensory perception of chemical stimulus

1 reference

8 April 2019

Expression of receptors for C5a anaphylatoxin (CD88) on human bronchial epithelial cells: enhancement of C5a-mediated release of IL-8 upon exposure to cigarette smoke

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21730

positive regulation of vascular endothelial growth factor production

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21730

cell proliferation in hindbrain

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21730

positive regulation of macrophage chemotaxis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21730

3 references

8 April 2019

Molecular cloning and characterization of the human anaphylatoxin C3a receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21730

8 April 2019

Expression cloning of a receptor for C5a anaphylatoxin on differentiated HL-60 cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21730

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21730

defense response to Gram-positive bacterium

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21730

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21730

regulation of complement activation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21730

phospholipase C-activating G protein-coupled receptor signaling pathway

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21730

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21730

neutrophil degranulation

1 reference

8 April 2019

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P21730&geneProductId=UniProtKB:P21730

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P21730&geneProductId=UniProtKB:P21730

positive regulation of cytosolic calcium ion concentration

3 references

8 April 2019

Molecular cloning and characterization of the human anaphylatoxin C3a receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21730

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21730

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21730

complement component C5a signaling pathway

1 reference

8 April 2019

Cloning and characterization of a rabbit ortholog of human Galpha16 and mouse G(alpha)15

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21730

complement receptor mediated signaling pathway

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21730

http://purl.uniprot.org/uniprot/P21730

Gene Atlas image

PBB GE C5AR1 220088 at fs.png
732 × 530; 8 KB

0 references

exact match

1 reference

GPCR, rhodopsin-like, 7TM

Identifiers.org

has part(s)

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P21730

Identifiers

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

0 references

Microsoft Academic ID

0 references

1 reference

26 January 2022

https://docs.openalex.org/download-snapshot/snapshot-data-format

Transporter Classification Database ID

9.A.14.13.26

2 references

Transporter Classification database

retrieved

13 March 2020