(Q5009956)

Protein kinase domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Protein kinase, ATP binding site, protein family

1 reference

based on heuristic

inferred from protein domain or family

Serine/threonine-protein kinase, active site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76039

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76039

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76039

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76039

8 April 2019

Functional consequences of mutations in CDKL5, an X-linked gene involved in infantile spasms and mental retardation

GOA

curator

HUGO Gene Nomenclature Committee

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76039

cyclin-dependent protein serine/threonine kinase activity

IDA

1 reference

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O76039&geneProductId=UniProtKB:O76039

cyclin-dependent protein serine/threonine kinase activity

IBA

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76039

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76039

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76039

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76039

perinuclear region of cytoplasm

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76039

1 reference

8 April 2019

CDKL Family Kinases Have Evolved Distinct Structural Features and Ciliary Function.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76039

1 reference

8 April 2019

CDKL Family Kinases Have Evolved Distinct Structural Features and Ciliary Function.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76039

1 reference

8 April 2019

CDKL Family Kinases Have Evolved Distinct Structural Features and Ciliary Function.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76039

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76039

microtubule organizing center

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76039

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76039

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76039

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76039

8 April 2019

Functional consequences of mutations in CDKL5, an X-linked gene involved in infantile spasms and mental retardation

GOA

curator

HUGO Gene Nomenclature Committee

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76039

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76039

CDKL5 ensures excitatory synapse stability by reinforcing NGL-1-PSD95 interaction in the postsynaptic compartment and is impaired in patient iPSC-derived neurons.

IBA

glutamatergic synapse

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76039

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76039

8 April 2019

CDKL5 ensures excitatory synapse stability by reinforcing NGL-1-PSD95 interaction in the postsynaptic compartment and is impaired in patient iPSC-derived neurons.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76039

8 April 2019

CDKL5 ensures excitatory synapse stability by reinforcing NGL-1-PSD95 interaction in the postsynaptic compartment and is impaired in patient iPSC-derived neurons.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76039

postsynaptic density, intracellular component

EXP

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76039

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76039

protein autophosphorylation

1 reference

8 April 2019

Functional consequences of mutations in CDKL5, an X-linked gene involved in infantile spasms and mental retardation

GOA

curator

HUGO Gene Nomenclature Committee

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76039

positive regulation of axon extension

IDA

regulation of dendrite development

positive regulation of dendritic spine development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76039

regulation of cilium assembly

1 reference

8 April 2019

CDKL Family Kinases Have Evolved Distinct Structural Features and Ciliary Function.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76039

IMP

regulation of cell cycle

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76039

Identification and characterization of a novel serine-threonine kinase gene from the Xp22 region

protein phosphorylation

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76039

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76039

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76039

regulation of postsynapse organization

IBA

3 references

8 April 2019

CDKL5 ensures excitatory synapse stability by reinforcing NGL-1-PSD95 interaction in the postsynaptic compartment and is impaired in patient iPSC-derived neurons.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76039

8 April 2019

CDKL5 ensures excitatory synapse stability by reinforcing NGL-1-PSD95 interaction in the postsynaptic compartment and is impaired in patient iPSC-derived neurons.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76039

8 April 2019

CDKL5 ensures excitatory synapse stability by reinforcing NGL-1-PSD95 interaction in the postsynaptic compartment and is impaired in patient iPSC-derived neurons.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O76039

http://purl.uniprot.org/uniprot/O76039

EXP

exact match

1 reference

serine/threonine-protein kinase, active site

Identifiers.org

has part(s)

1 reference

protein kinase, ATP binding site

1 reference

protein kinase domain

1 reference