(Q50251177)

English

HSP90 [cytosol]

An instance of macromolecular complex in Homo sapiens with Reactome ID (R-HSA-1221657)

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1 reference

8 July 2022

1 reference

8 July 2022

Ligand-responsive p-6Y-EGFR mutants sensitive to non-covalent TKIs:HSP90:CDC37 [plasma membrane]

1 reference

8 July 2022

ERBB2 KD mutants (lapatinib resistant):ERBIN:HSP90:CDC37 [plasma membrane]

1 reference

8 July 2022

ERBB2 TMD/JMD mutants:ERBIN:HSP90:CDC37 [plasma membrane]

1 reference

8 July 2022

HSP90:HSP90 [cytosol]

1 reference

8 July 2022

ERBB2 KD mutants (neratinib resistant):ERBIN:HSP90:CDC37 [plasma membrane]

1 reference

8 July 2022

ERBB2 T798M:ERBIN:HSP90:CDC37 [plasma membrane]

1 reference

8 July 2022

ERBB2 TMD/JMD mutants (trastuzumab):trastuzumab:ERBIN:HSP90:CDC37 [plasma membrane]

1 reference

8 July 2022

ERBB2 TMD/JMD mutants (trastuzumab):ERBIN:HSP90:CDC37 [plasma membrane]

1 reference

8 July 2022

ERBB2 forms heterodimers with ligand-activated ERBB receptors: EGFR, ERBB3 and ERBB4

1 reference

8 July 2022

ERBB2 KD mutants:ERBIN:HSP90:CDC37 [plasma membrane]

1 reference

8 July 2022

ERBB2 homodimerization

1 reference

8 July 2022

ERBB2 KD mutants (osimertinib resistant):ERBIN:HSP90:CDC37 [plasma membrane]

1 reference

8 July 2022

EGFRvIII mutant binds chaperone proteins HSP90 and CDC37.

1 reference

8 July 2022

Ub-ERBB2:ERBIN:Ub-HSP90:CDC37 [plasma membrane]

1 reference

8 July 2022

ERBB2 KD mutants (AEE788 resistant):ERBIN:HSP90:CDC37 [plasma membrane]

1 reference

8 July 2022

Ub-ERBB2:ERBIN:HSP90:CDC37 [plasma membrane]

1 reference

8 July 2022

EGF:Ligand-responsive EGFR mutants resistant to non-covalent TKIs:HSP90:CDC37 [plasma membrane]

1 reference

8 July 2022

EGF:Ligand-responsive p-6Y-EGFR mutants resistant to non-covalent TKIs:HSP90:CDC37 [plasma membrane]

1 reference

8 July 2022

Binding of ligand-responsive EGFR mutants to chaperoning proteins HSP90 and CDC37

1 reference

8 July 2022

ERBB2 TMD/JMD mutants (pertuzumab resistant):ERBIN:HSP90:CDC37 [plasma membrane]

1 reference

8 July 2022

ERBB2 R678Q:ERBIN:HSP90:CDC37 [plasma membrane]

1 reference

8 July 2022

ERBB2 R678Q:pertuzumab:ERBIN:HSP90:CDC37 [plasma membrane]

1 reference

8 July 2022

ERBB2 T862A:ERBIN:HSP90:CDC37 [plasma membrane]

1 reference

8 July 2022

EGF:Ligand-responsive EGFR mutants sensitive to non-covalent TKIs:HSP90:CDC37 [plasma membrane]

1 reference

8 July 2022

EGF:Ligand-responsive p-6Y-EGFR mutants sensitive to non-covalent TKIs:HSP90:CDC37 [plasma membrane]

1 reference

8 July 2022

Phospho-EGFRvIIImut:HSP90:CDC37 [plasma membrane]

1 reference

8 July 2022

ERBB2:trastuzumab:ERBIN:HSP90:CDC37 [plasma membrane]

1 reference

8 July 2022

Ligand-responsive EGFR mutants resistant to non-covalent TKIs:HSP90:CDC37 [plasma membrane]

1 reference

8 July 2022

Ligand-responsive p-6Y-EGFR mutants resistant to non-covalent TKIs:HSP90:CDC37 [plasma membrane]

1 reference

8 July 2022

HSP90 is inactivated by binding to benzaquinoid ansamycins

1 reference

8 July 2022

Ligand-responsive EGFR mutants sensitive to non-covalent TKIs:HSP90:CDC37 [plasma membrane]

1 reference

8 July 2022

HSP90:Benzoquinoid ansamycins [cytosol]

1 reference

8 July 2022

ERBB2:ERBIN:HSP90:CDC37 [plasma membrane]

1 reference

8 July 2022

ERBB2 KD mutants (trastuzumab sensitive):trastuzumab:ERBIN:HSP90:CDC37 [plasma membrane]

1 reference

8 July 2022

ERBB2 TMD/JMD mutants hetrodimerize

1 reference

8 July 2022

ERBB2 ECD mutants:ERBIN:HSP90:CDC37 [plasma membrane]

1 reference

8 July 2022

ERBB2 KD mutants (trastuzumab sensitive):ERBIN:HSP90:CDC37 [plasma membrane]

1 reference

8 July 2022

ERBB2 KD mutants heterodimerize

1 reference

8 July 2022

ERBB2:pertuzumab:ERBIN:HSP90:CDC37 [plasma membrane]

1 reference

8 July 2022

ERBB2 TMD/JMD mutants (TKI sensitive):ERBIN:HSP90:CDC37 [plasma membrane]

1 reference

8 July 2022

EGFRvIII mutant:HSP90:CDC37 [plasma membrane]

1 reference

8 July 2022

ERBB2 KD mutants:TKIs:ERBIN:HSP90:CDC37 [plasma membrane]

1 reference

8 July 2022

ERBB2:TKIs:ERBIN:HSP90:CDC37 [plasma membrane]

1 reference

8 July 2022

ERBB2 KD mutants (TKI sensitive):ERBIN:HSP90:CDC37 [plasma membrane]

1 reference

8 July 2022

ERBB2 TMD/JMD mutants (TKI sensitive):TKI:ERBIN:HSP90:CDC37 [plasma membrane]

1 reference

8 July 2022

ERBB2 ECD mutants heterodimerize with EGFR

1 reference

8 July 2022

ERBB2 KD mutants (trastuzumab resistant):ERBIN:HSP90:CDC37 [plasma membrane]

1 reference

8 July 2022

ERBB2 T733I:ERBIN:HSP90:CDC37 [plasma membrane]

1 reference

8 July 2022

RIPK3:HSP90:CDC37 [cytosol]

1 reference

8 July 2022

RIPK3 binds HSP90:CDC37

1 reference

8 July 2022

MLKL binds HSP90:CDC37

1 reference

8 July 2022

MLKL:HSP90:CDC37 [cytosol]

1 reference

8 July 2022

1 reference

8 July 2022

https://identifiers.org/reactome:R-HSA-1221657

1 reference

8 July 2022

Heat shock protein 90 alpha family class A member 1

quantity

2

1 reference

8 July 2022

Identifiers

1 reference

8 July 2022

(Q50251177)

HSP90 [cytosol]

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Identifiers

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