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SIRP alpha binds CD47
An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-391158)
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Statements
instance of
biological process
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-391158
part of
Signal regulatory protein family interactions
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-391158
found in taxon
Homo sapiens
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-391158
exact match
https://identifiers.org/reactome:R-HSA-391158
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-391158
has part(s)
CD47 molecule
quantity
1
object has role
reactant
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-391158
Signal regulatory protein alpha
quantity
1
object has role
reactant
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-391158
SIRPA:CD47 [plasma membrane]
quantity
1
object has role
product
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-391158
cites work
Human signal-regulatory protein is expressed on normal, but not on subsets of leukemic myeloid cells and mediates cellular adhesion involving its counterreceptor CD47
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-391158
Paired receptor specificity explained by structures of signal regulatory proteins alone and complexed with CD47
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-391158
The structure of the macrophage signal regulatory protein alpha (SIRPalpha) inhibitory receptor reveals a binding face reminiscent of that used by T cell receptors
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-391158
Structure of Signal-regulatory Protein : A LINK TO ANTIGEN RECEPTOR EVOLUTION
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-391158
Functional elements on SIRPalpha IgV domain mediate cell surface binding to CD47.
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-391158
Identifiers
Reactome ID
R-HSA-391158
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-391158
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