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CDKN1A (p21) prevents association of Cyclin A:Cdk2 with Cdh1
An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-3788708)
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Statements
instance of
biological process
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-3788708
part of
Senescence-Associated Secretory Phenotype (SASP)
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-3788708
found in taxon
Homo sapiens
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-3788708
exact match
https://identifiers.org/reactome:R-HSA-3788708
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-3788708
has part(s)
CCNA:p-T160-CDK2 [nucleoplasm]
quantity
1
object has role
reactant
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-3788708
Cdh1:phospho-APC/C complex [nucleoplasm]
quantity
1
object has role
reactant
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-3788708
Cyclin A:phospho-Cdk(Thr 160):Cdh1:phosho-APC/C complex [nucleoplasm]
quantity
1
object has role
product
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-3788708
Cyclin A:Cdk2:p21/p27 complex [nucleoplasm]
quantity
1
object has role
modifier
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-3788708
cites work
A conserved cyclin-binding domain determines functional interplay between anaphase-promoting complex-Cdh1 and cyclin A-Cdk2 during cell cycle progression
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-3788708
DNA damage signaling triggers degradation of histone methyltransferases through APC/C(Cdh1) in senescent cells
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-3788708
Identifiers
Reactome ID
R-HSA-3788708
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-3788708
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