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COPRS:CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-4 of histone H4 (H4R3)
An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-5205861)
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Statements
instance of
biological process
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5205861
part of
RMTs methylate histone arginines
1 reference
stated in
Reactome
retrieved
13 July 2022
Reactome ID
R-HSA-5205861
found in taxon
Homo sapiens
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5205861
exact match
https://identifiers.org/reactome:R-HSA-5205861
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5205861
has part(s)
S-adenosyl-L-methionine
quantity
1
object has role
reactant
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5205861
MeR4-HIST1H4, HIST1H4 [nucleoplasm]
quantity
1
object has role
reactant
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5205861
S-adenosyl-L-homocysteine
quantity
1
object has role
product
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5205861
Me2sR4-HIST1H4, MeR4-HIST1H4 [nucleoplasm]
quantity
1
object has role
product
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5205861
CCND1:CDK4:PRMT5:pT5-WDR77:COPRS [nucleoplasm]
quantity
1
object has role
modifier
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5205861
SWI/SNF chromatin remodelling complex:PRMT5:pT5-WDR77 [nucleoplasm]
quantity
1
object has role
modifier
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5205861
cites work
Human SWI/SNF-associated PRMT5 methylates histone H3 arginine 8 and negatively regulates expression of ST7 and NM23 tumor suppressor genes
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5205861
The histone-binding protein COPR5 is required for nuclear functions of the protein arginine methyltransferase PRMT5
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5205861
Identifiers
Reactome ID
R-HSA-5205861
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5205861
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