(Q50287331)

English

TP53BP1 associates with H4K20Me2 at DNA DSBs

An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-5693566)

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biological process

1 reference

8 July 2022

Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks

1 reference

8 July 2022

1 reference

8 July 2022

https://identifiers.org/reactome:R-HSA-5693566

1 reference

8 July 2022

DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4 [nucleoplasm]

1

object of statement has role

1 reference

8 July 2022

Tumor protein p53 binding protein 1

1

object of statement has role

1 reference

8 July 2022

DNA DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:TP53BP1 [nucleoplasm]

1

object of statement has role

1 reference

8 July 2022

RNF8- and RNF168-dependent degradation of KDM4A/JMJD2A triggers 53BP1 recruitment to DNA damage sites

1 reference

8 July 2022

MMSET regulates histone H4K20 methylation and 53BP1 accumulation at DNA damage sites

1 reference

8 July 2022

Identifiers

1 reference

8 July 2022

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