(Q50287377)

English

Cleavage of Holliday junctions by GEN1 or SLX1A:SLX4:MUS81:EME1,(MUS81:EME2)

An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-5693584)

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biological process

1 reference

8 July 2022

Resolution of D-loop Structures through Holliday Junction Intermediates

1 reference

8 July 2022

1 reference

8 July 2022

https://identifiers.org/reactome:R-HSA-5693584

1 reference

8 July 2022

Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm]

1

object of statement has role

1 reference

8 July 2022

Cleaved Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm]

1

object of statement has role

1 reference

8 July 2022

SLX1A:SLX4:MUS81:EME1,(MUS81:EME2),GEN1 [nucleoplasm]

1

object of statement has role

1 reference

8 July 2022

Coordinated actions of SLX1-SLX4 and MUS81-EME1 for Holliday junction resolution in human cells

1 reference

8 July 2022

Roles of SLX1-SLX4, MUS81-EME1, and GEN1 in avoiding genome instability and mitotic catastrophe

1 reference

8 July 2022

Identifiers

1 reference

8 July 2022

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