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UVSSA:USP7 deubiquitinates ERCC6
An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-6782069)
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Statements
instance of
biological process
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-6782069
part of
Formation of TC-NER Pre-Incision Complex
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-6782069
found in taxon
Homo sapiens
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-6782069
exact match
https://identifiers.org/reactome:R-HSA-6782069
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-6782069
has part(s)
water
quantity
1
object has role
reactant
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-6782069
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:Ub:ERCC6:ERCC8:DDB1:CUL4:RBX1:UVSSA:USP7:XAB2 complex:XPA:TCEA1:HMGN1:EP300 [nucleoplasm]
quantity
1
object has role
reactant
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-6782069
TC-NER pre-incision complex [nucleoplasm]
quantity
1
object has role
product
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-6782069
Ub [nucleoplasm]
quantity
1
object has role
product
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-6782069
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:Ub:ERCC6:ERCC8:DDB1:CUL4:RBX1:UVSSA:USP7:XAB2 complex:XPA:TCEA1:HMGN1:EP300 [nucleoplasm]
quantity
1
object has role
modifier
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-6782069
cites work
UV-sensitive syndrome protein UVSSA recruits USP7 to regulate transcription-coupled repair
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-6782069
KIAA1530 protein is recruited by Cockayne syndrome complementation group protein A (CSA) to participate in transcription-coupled repair (TCR).
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-6782069
Mutations in UVSSA cause UV-sensitive syndrome and impair RNA polymerase IIo processing in transcription-coupled nucleotide-excision repair
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-6782069
Mutations in UVSSA cause UV-sensitive syndrome and destabilize ERCC6 in transcription-coupled DNA repair
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-6782069
Identifiers
Reactome ID
R-HSA-6782069
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-6782069
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