(Q50287564)

English

Activation of Cdc42

An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-418850)

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Statements

biological process

1 reference

8 July 2022

DCC mediated attractive signaling

1 reference

8 July 2022

1 reference

8 July 2022

https://identifiers.org/reactome:R-HSA-418850

1 reference

8 July 2022

CDC42:GDP [cytosol]

1

object has role

1 reference

8 July 2022

NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO [plasma membrane]

1

object has role

1 reference

8 July 2022

NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO:CDC42:GTP [plasma membrane]

1

object has role

1 reference

8 July 2022

NTN1:p-Y1420-DCC oligomer:p-Y397-PTK2:MyrG-p-Y419-SRC,MyrG-p-Y420-FYN:NCK1:DOCK1,TRIO [plasma membrane]

1

object has role

1 reference

8 July 2022

1

object has role

1 reference

8 July 2022

1

object has role

1 reference

8 July 2022

The netrin-1 receptor DCC promotes filopodia formation and cell spreading by activating Cdc42 and Rac1.

1 reference

8 July 2022

Deleted in colorectal cancer binding netrin-1 mediates cell substrate adhesion and recruits Cdc42, Rac1, Pak1, and N-WASP into an intracellular signaling complex that promotes growth cone expansion

1 reference

8 July 2022

Identifiers

1 reference

8 July 2022

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