(Q50288600)

English

SOS-mediated nucleotide exchange of RAS (mediated by GRB2:SOS1 in complex with ligand-responsive p-6Y-EGFR mutants)

An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-1225951)

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8 July 2022

Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants

1 reference

8 July 2022

1 reference

8 July 2022

https://identifiers.org/reactome:R-HSA-1225951

1 reference

8 July 2022

p21 RAS:GDP [plasma membrane]

quantity

1

object of statement has role

1 reference

8 July 2022

p21 RAS:GTP [plasma membrane]

quantity

1

object of statement has role

1 reference

8 July 2022

Ligand-responsive p-6Y-EGFR mutants:GRB2:SOS1 [plasma membrane]

quantity

1

object of statement has role

1 reference

8 July 2022

1

object of statement has role

1 reference

8 July 2022

1

object of statement has role

1 reference

8 July 2022

Epidermal growth factor receptors harboring kinase domain mutations associate with the heat shock protein 90 chaperone and are destabilized following exposure to geldanamycins

1 reference

8 July 2022

EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy

1 reference

8 July 2022

Gefitinib-sensitizing EGFR mutations in lung cancer activate anti-apoptotic pathways

1 reference

8 July 2022

Identifiers

1 reference

8 July 2022

(Q50288600)

SOS-mediated nucleotide exchange of RAS (mediated by GRB2:SOS1 in complex with ligand-responsive p-6Y-EGFR mutants)

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