(Q50289170)

English

Defective ACTH does not bind MCR2

An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-5603251)

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Statements

biological process

1 reference

8 July 2022

Defective ACTH causes obesity and POMCD

1 reference

8 July 2022

1 reference

8 July 2022

https://identifiers.org/reactome:R-HSA-5603251

1 reference

8 July 2022

ACTH mutants [extracellular region]

1

object has role

1 reference

8 July 2022

Melanocortin 2 receptor

1

object has role

1 reference

8 July 2022

Severe early-onset obesity, adrenal insufficiency and red hair pigmentation caused by POMC mutations in humans

1 reference

8 July 2022

A missense mutation disrupting a dibasic prohormone processing site in pro-opiomelanocortin (POMC) increases susceptibility to early-onset obesity through a novel molecular mechanism

1 reference

8 July 2022

Obesity due to proopiomelanocortin deficiency: three new cases and treatment trials with thyroid hormone and ACTH4-10.

1 reference

8 July 2022

Identifiers

1 reference

8 July 2022

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