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Defective ACTH does not bind MCR2
An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-5603251)
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Statements
instance of
biological process
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5603251
part of
Defective ACTH causes obesity and POMCD
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5603251
found in taxon
Homo sapiens
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5603251
exact match
https://identifiers.org/reactome:R-HSA-5603251
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5603251
has part(s)
ACTH mutants [extracellular region]
quantity
1
object has role
reactant
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5603251
Melanocortin 2 receptor
quantity
1
object has role
reactant
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5603251
cites work
Severe early-onset obesity, adrenal insufficiency and red hair pigmentation caused by POMC mutations in humans
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5603251
A missense mutation disrupting a dibasic prohormone processing site in pro-opiomelanocortin (POMC) increases susceptibility to early-onset obesity through a novel molecular mechanism
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5603251
Obesity due to proopiomelanocortin deficiency: three new cases and treatment trials with thyroid hormone and ACTH4-10.
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5603251
Identifiers
Reactome ID
R-HSA-5603251
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5603251
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