(Q50289623)

English

Furin cleaves ANTXR2-bound pagA to yield pagA(197-794)

An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-5210912)

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Statements

biological process

1 reference

8 July 2022

Uptake and function of anthrax toxins

1 reference

8 July 2022

1 reference

8 July 2022

https://identifiers.org/reactome:R-HSA-5210912

1 reference

8 July 2022

pagA:ANTXR2 [plasma membrane]

1

object has role

1 reference

8 July 2022

anthrax protective antigen

1

object has role

1 reference

8 July 2022

pagA(197-794):ANTXR2 [plasma membrane]

1

object has role

1 reference

8 July 2022

Furin, paired basic amino acid cleaving enzyme

1

object has role

1 reference

8 July 2022

FURIN:FURIN inhibitors [plasma membrane]

1

object has role

1 reference

8 July 2022

Anthrax toxin protective antigen is activated by a cell surface protease with the sequence specificity and catalytic properties of furin

1 reference

8 July 2022

Human furin is a calcium-dependent serine endoprotease that recognizes the sequence Arg-X-X-Arg and efficiently cleaves anthrax toxin protective antigen

1 reference

8 July 2022

Identifiers

1 reference

8 July 2022

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