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English
Anthrax lef cleaves target cell MAP2K3 (MEK3)
An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-5211400)
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Statements
instance of
biological process
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5211400
part of
Uptake and function of anthrax toxins
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5211400
found in taxon
Homo sapiens
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5211400
exact match
https://identifiers.org/reactome:R-HSA-5211400
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5211400
has part(s)
mitogen-activated protein kinase kinase 3
quantity
1
object has role
reactant
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5211400
mitogen-activated protein kinase kinase 3
quantity
1
object has role
product
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5211400
lef [cytosol]
quantity
1
object has role
modifier
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5211400
cites work
Anthrax toxin lethal factor contains a zinc metalloprotease consensus sequence which is required for lethal toxin activity
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5211400
Anthrax lethal factor cleaves MKK3 in macrophages and inhibits the LPS/IFNgamma-induced release of NO and TNFalpha
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5211400
Identifiers
Reactome ID
R-HSA-5211400
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-5211400
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