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(Q50290119)
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SMAD2/3 activation induces binding of RNF111/SMURF2 to SKI/SKIL
An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-2186741)
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Statements
instance of
biological process
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-2186741
part of
Downregulation of SMAD2/3:SMAD4 transcriptional activity
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-2186741
found in taxon
Homo sapiens
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-2186741
exact match
https://identifiers.org/reactome:R-HSA-2186741
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-2186741
has part(s)
p-2S-SMAD2,3:SMAD4:SKI/SKIL:NCOR [nucleoplasm]
quantity
1
object has role
reactant
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-2186741
RNF111/SMURF2 [nucleoplasm]
quantity
1
object has role
reactant
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-2186741
p-2S-SMAD2,3:SMAD4:SKI/SKIL:NCOR:RNF111/SMURF2 [nucleoplasm]
quantity
1
object has role
product
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-2186741
cites work
Arkadia activates Smad3/Smad4-dependent transcription by triggering signal-induced SnoN degradation
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-2186741
TGF-beta induces assembly of a Smad2-Smurf2 ubiquitin ligase complex that targets SnoN for degradation
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-2186741
Identifiers
Reactome ID
R-HSA-2186741
1 reference
stated in
Reactome
retrieved
8 July 2022
Reactome ID
R-HSA-2186741
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